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Results for “Langerhans Cell Histiocytoses”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)WithdrawnNCT03687476
What this trial is testing

Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease

Who this might be right for
Niemann-Pick Disease, Type C
Vtesse, LLC, a Mallinckrodt Pharmaceuticals Company
Not applicableNot Yet RecruitingNCT06734624
What this trial is testing

The Microbiome in Blood Cancer and HLH

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)Follicular Lymphoma (FL)Haemophagocytic Lymphohistiocytosis
University of Nottingham 750
Large-scale testing (Phase 3)Looking for participantsNCT07339345
What this trial is testing

Prospective Single-Arm Clinical Trial of GO Regimen for HLH.

Who this might be right for
Lymphohistiocytosis, Hemophagocytic
Beijing Friendship Hospital 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07660783
What this trial is testing

Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases

Who this might be right for
Bone Marrow FailureHemoglobinopathiesPrimary Immune Deficiency (PID)+4 more
Fred Hutchinson Cancer Center 40
Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Study completedNCT03471143
What this trial is testing

Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C

Who this might be right for
Niemann-Pick Disease, Type C
Washington University School of Medicine 4
Large-scale testing (Phase 3)Study completedNCT01371825
What this trial is testing

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Who this might be right for
Lysosomal Acid Lipase DeficiencyWolman Disease
Alexion Pharmaceuticals, Inc. 9
Testing effectiveness (Phase 2)Looking for participantsNCT07187167
What this trial is testing

Efficacy and Safety of the RD Regimen(Lenalidomide, Dexamethasone) for Rosai-Dorfman Disease

Who this might be right for
Rosai-Dorfman Disease
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 40
Not applicableLooking for participantsNCT07800234
What this trial is testing

Establishing a National Egyptian HLH Registry (NEHR)

Who this might be right for
HLHHemophagocytic Lymphohistiocytoses
Ain Shams University 100
Not applicableStudy completedNCT04902807
What this trial is testing

Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

Who this might be right for
Autoimmune Lymphoproliferative SyndromeAutoimmune CytopeniaAutoimmune Diseases+17 more
Institut National de la Santé Et de la Recherche Médicale, France 325
Large-scale testing (Phase 3)Study completedNCT02612129
What this trial is testing

Arimoclomol Prospective Study in Participants Diagnosed With Niemann-Pick Disease Type C

Who this might be right for
Niemann-Pick Disease, Type C
ZevraDenmark 50
Not applicableLooking for participantsNCT05915208
What this trial is testing

Histiocytic Disorder Follow-up Study

Who this might be right for
HistiocytosisLangerhans Cell HistiocytosisErdheim-Chester Disease+3 more
University of Alabama at Birmingham 6,000
Post-approval studies (Phase 4)Study completedNCT05744063
What this trial is testing

A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese Patients

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 13
Not applicableStudy completedNCT02113917
What this trial is testing

Children and Adult Hemophagocytic Syndrome (HLHa)

Who this might be right for
Hemophagocytic Syndrome
Assistance Publique - Hôpitaux de Paris 204
Early research (Phase 1)UnknownNCT04326348
What this trial is testing

TQ05105 Tablets in Subjects With Hemophagocytic Lymphohistiocytosis（HLH）

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02425904
What this trial is testing

Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute 25
Not applicableAvailableNCT04316637
What this trial is testing

Early Access Program With Arimoclomol in US Patients With NPC

Who this might be right for
Niemann-Pick Disease, Type C
ZevraDenmark
Not applicableLooking for participantsNCT05898477
What this trial is testing

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

Who this might be right for
LymphomaHemophagocytic Lymphohistiocytoses
University of Alabama at Birmingham 2,000
Testing effectiveness (Phase 2)Study completedNCT02292654
What this trial is testing

Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency

Who this might be right for
Sphingomyelin Lipidosis
Genzyme, a Sanofi Company 20
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