Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Langerhans Cell Histiocytosis (LCH)”

84 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 84 results

Early research (Phase 1)Study completedNCT01471067
What this trial is testing

Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

Who this might be right for
Blood And Marrow TransplantationLeukemiaLymphoma+2 more
M.D. Anderson Cancer Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06078969
What this trial is testing

Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence

Who this might be right for
Langerhans Cell Histiocytosis of Bone
Shanghai Changzheng Hospital 118
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)UnknownNCT00008164
What this trial is testing

Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia

Who this might be right for
Childhood Langerhans Cell HistiocytosisLeukemiaLymphoma+3 more
Herbert Irving Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT07022834
What this trial is testing

Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children

Who this might be right for
Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital 20
Testing effectiveness (Phase 2)Study completedNCT02389400
What this trial is testing

Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis
Peking Union Medical College Hospital 43
Not applicableLooking for participantsNCT04627090
What this trial is testing

LCH in Adults: a Collaborative, Prospective-retrospective, Observational Study

Who this might be right for
Langerhans Cell Histiocytosis
Gruppo Italiano Malattie EMatologiche dell'Adulto 186
Testing effectiveness (Phase 2)Looking for participantsNCT04943224
What this trial is testing

Optimization of the Time and Dosage of Trametinib in BRAF Negative Juvenile Patients

Who this might be right for
Histiocytosis
Anna Raciborska 12
Not applicableActive Not RecruitingNCT04100408
What this trial is testing

Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH)

Who this might be right for
Histiocytosis, Langerhans-Cell
Children's Oncology Group 647
Not applicableLooking for participantsNCT07371182
What this trial is testing

Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions

Who this might be right for
Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital 62
Testing effectiveness (Phase 2)Looking for participantsNCT06153173
What this trial is testing

Mirdametinib in Histiocytic Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more
Children's Hospital Medical Center, Cincinnati 40
Testing effectiveness (Phase 2)UnknownNCT01473797
What this trial is testing

Evaluation of Efficacy and Tolerance of Cladribine in Symptomatic Pulmonary Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis of Lung
Assistance Publique - Hôpitaux de Paris 10
Post-approval studies (Phase 4)Active Not RecruitingNCT03975829
What this trial is testing

Pediatric Long-Term Follow-up and Rollover Study

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+20 more
Novartis Pharmaceuticals 163
Testing effectiveness (Phase 2)Looking for participantsNCT06582745
What this trial is testing

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Who this might be right for
Langerhans Cell Histiocytosis
Cook Children's Health Care System 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Testing effectiveness (Phase 2)Study completedNCT02281760
What this trial is testing

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Who this might be right for
BRAF V600E Mutation
National Human Genome Research Institute (NHGRI) 9
Large-scale testing (Phase 3)Looking for participantsNCT04773366
What this trial is testing

A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol

Who this might be right for
Langerhans Cell Histiocytosis
Shanghai Children's Medical Center 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Large-scale testing (Phase 3)Looking for participantsNCT02670707
What this trial is testing

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Who this might be right for
Langerhans Cell Histiocytosis
Baylor College of Medicine 124
Load More Results