Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Langerhans Cell Histiocytosis (LCH)”

86 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 86 results

Testing effectiveness (Phase 2)Looking for participantsNCT04079179
What this trial is testing

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Who this might be right for
Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Carl Allen 90
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Not applicableEnded earlyNCT00008216
What this trial is testing

Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Adult Langerhans Cell HistiocytosisChildhood Langerhans Cell HistiocytosisLeukemia+4 more
Columbia University 48
Not applicableStudy completedNCT01651507
What this trial is testing

Evaluation of Outcome of Adult Pulmonary Langerhans Cell Histiocytosis Based on Lung HRCT and Lung Function

Who this might be right for
Pulmonary Langerhans Cell Histiocytosis
Assistance Publique - Hôpitaux de Paris 49
Not applicableLooking for participantsNCT04665674
What this trial is testing

Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study

Who this might be right for
HistiocytosisHistiocytosis, Langerhans-CellHistiocytosis Pulmonary
Assistance Publique - Hôpitaux de Paris 500
Testing effectiveness (Phase 2)Looking for participantsNCT06153173
What this trial is testing

Mirdametinib in Histiocytic Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more
Children's Hospital Medical Center, Cincinnati 40
Large-scale testing (Phase 3)Active Not RecruitingNCT02205762
What this trial is testing

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis
North American Consortium for Histiocytosis 1,400
Not applicableUnknownNCT03093727
What this trial is testing

Characterization of Pulmonary Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytoses
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 20
Testing effectiveness (Phase 2)Looking for participantsNCT04943224
What this trial is testing

Optimization of the Time and Dosage of Trametinib in BRAF Negative Juvenile Patients

Who this might be right for
Histiocytosis
Anna Raciborska 12
Testing effectiveness (Phase 2)WithdrawnNCT01796405
What this trial is testing

Clofarabine for Langerhans in Pedi

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute
Testing effectiveness (Phase 2)Active Not RecruitingNCT03698994
What this trial is testing

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Ependymal TumorRecurrent Ewing Sarcoma+33 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Study completedNCT03096782
What this trial is testing

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more
M.D. Anderson Cancer Center 6
Not applicableUnknownNCT00483925
What this trial is testing

Cardiovascular Risk Factors and LCH in Adults

Who this might be right for
Histiocytosis, Langerhans-Cell
Laikο General Hospital, Athens
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Early research (Phase 1)Study completedNCT00890747
What this trial is testing

Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAcute Undifferentiated Leukemia+82 more
National Cancer Institute (NCI) 42
Not applicableLooking for participantsNCT07371182
What this trial is testing

Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions

Who this might be right for
Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital 62
Not applicableStudy completedNCT01225601
What this trial is testing

Prospective Evaluation of Adult Pulmonary Langerhans Cell Histiocytosis

Who this might be right for
Adult Pulmonary Langerhans Cell Histiocytosis
Assistance Publique - Hôpitaux de Paris 62
Large-scale testing (Phase 3)Looking for participantsNCT04943211
What this trial is testing

Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging

Who this might be right for
Histiocytosis
Anna Raciborska 150
Load More Results