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Results for “Large B-Cell Lymphoma (LBCL)”

51 trials

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Showing 20 of 51 results

Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Testing effectiveness (Phase 2)Temporarily pausedNCT04855253
What this trial is testing

Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL

Who this might be right for
DLBCLDiffuse Large B Cell LymphomaHigh-grade B-cell Lymphoma+1 more
Masonic Cancer Center, University of Minnesota 30
Testing effectiveness (Phase 2)Temporarily pausedNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06500273
What this trial is testing

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Allogene Therapeutics 250
Not applicableLooking for participantsNCT06830759
What this trial is testing

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Who this might be right for
Diffuse Large B-cell LymphomaFollicular Lymphoma
AbbVie 700
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07814001
What this trial is testing

Epcoritamab Plus Lenalidomide in Relapsed/Refractory Large B-cell Lymphoma After Second-Line CAR T-cell Therapy

Who this might be right for
Refractory Diffuse Large B-Cell Lymphoma (DLBCL)Refractory Large B-cell Lymphoma (LBCL)Refractory T-cell/Histiocyte-rich Large B-cell Lymphoma+3 more
The Lymphoma Academic Research Organisation 55
Testing effectiveness (Phase 2)Looking for participantsNCT06479356
What this trial is testing

CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaLarge B-cell Lymphoma
Shanghai Ming Ju Biotechnology Co., Ltd. 12
Testing effectiveness (Phase 2)Looking for participantsNCT06905509
What this trial is testing

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements+11 more
University of California, Davis
Early research (Phase 1)Study completedNCT03939026
What this trial is testing

Safety and Efficacy of ALLO-501 Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell or Follicular Lymphoma

Who this might be right for
Relapsed/Refractory Large B Cell LymphomaRelapsed/Refractory Follicular Lymphoma
Allogene Therapeutics 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07613788
What this trial is testing

Rimegepant Plus Glofitamab and CD19 CAR-T Therapy in R/R LBCL

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)
Ruijin Hospital 100
Testing effectiveness (Phase 2)Looking for participantsNCT04844866
What this trial is testing

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Who this might be right for
Diffuse Large B-cell Lymphoma
Miltenyi Biomedicine GmbH 213
Not applicableNot Yet RecruitingNCT06935136
What this trial is testing

Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel Injection as First-Line Therapy of High-Risk Large B-Cell Lymphoma

Who this might be right for
CAR-T Cell TherapyHigh-risk Large B-cell Lymphoma (LBCL)
Ruijin Hospital 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04416984
What this trial is testing

Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)

Who this might be right for
Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Allogene Therapeutics 160
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07567014
What this trial is testing

Emapalumab Prophylaxis of Bispecific T-Cell Engagers (BiTEs) Associated CRS and ICANS

Who this might be right for
Multiple MyelomaLarge B-cell Lymphoma (LBCL)
NYU Langone Health 60
Testing effectiveness (Phase 2)Ended earlyNCT05972720
What this trial is testing

Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
CancerRelapsed/Refractory Large B-cell Lymphoma (LBCL)
CARGO Therapeutics 101
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07593482
What this trial is testing

Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.

Who this might be right for
B-cell Lymphoma
Swiss Cancer Institute 92
Early research (Phase 1)Looking for participantsNCT07361224
What this trial is testing

Investigator Initiated Study to Assess the Safety of Combination of CLS-015 With Anti-CD-19 CAR-T Cells in Patients With Stable/Progressive Large B Cell Lymphoma at Lymphodepletion.

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Tel-Aviv Sourasky Medical Center 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03960840
What this trial is testing

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaDiffuse Large B-cell Lymphoma+2 more
Novartis Pharmaceuticals 217
Testing effectiveness (Phase 2)Looking for participantsNCT05464719
What this trial is testing

A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy

Who this might be right for
Large B-cell LymphomaLymphoma
M.D. Anderson Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06104592
What this trial is testing

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

Who this might be right for
Large B-cell LymphomaRelapsed Non-Hodgkin Lymphoma
H. Lee Moffitt Cancer Center and Research Institute 27
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