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Results for “Large B-Cell Lymphoma (LBCL)”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04416984
What this trial is testing

Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults with Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)

Who this might be right for
Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Allogene Therapeutics 160
Testing effectiveness (Phase 2)Looking for participantsNCT05464719
What this trial is testing

A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy

Who this might be right for
Large B-cell LymphomaLymphoma
M.D. Anderson Cancer Center 30
Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Large-scale testing (Phase 3)Looking for participantsNCT05605899
What this trial is testing

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

Who this might be right for
High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company 300
Testing effectiveness (Phase 2)Looking for participantsNCT06542250
What this trial is testing

Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

Who this might be right for
B-cell Malignancies
AstraZeneca 174
Testing effectiveness (Phase 2)Ended earlyNCT05714345
What this trial is testing

Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy

Who this might be right for
Relapsed/Refractory Large B Cell Lymphoma
Allogene Therapeutics 2
Testing effectiveness (Phase 2)Looking for participantsNCT06500273
What this trial is testing

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Allogene Therapeutics 250
Testing effectiveness (Phase 2)Looking for participantsNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06526793
What this trial is testing

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

Who this might be right for
B-cell Non-Hodgkin LymphomaFollicular Lymphoma (FL)Large B-Cell Lymphoma (LBCL)
AstraZeneca 240
Testing effectiveness (Phase 2)Active Not RecruitingNCT04844866
What this trial is testing

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Who this might be right for
Diffuse Large B-cell Lymphoma
Miltenyi Biomedicine GmbH 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07269639
What this trial is testing

Golcadomide, Poseltinib, and Rituximab for Relapsed/Refractory Diffuse Large B-cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Seoul National University Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT05641428
What this trial is testing

Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL

Who this might be right for
NHLDLBCL - Diffuse Large B Cell Lymphoma
University Medical Center Groningen 300
Testing effectiveness (Phase 2)Temporarily pausedNCT04855253
What this trial is testing

Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL

Who this might be right for
DLBCLDiffuse Large B Cell LymphomaHigh-grade B-cell Lymphoma+1 more
Masonic Cancer Center, University of Minnesota 30
Testing effectiveness (Phase 2)Looking for participantsNCT06287398
What this trial is testing

Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL

Who this might be right for
DLBCL - Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaHigh Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements+4 more
Australasian Leukaemia and Lymphoma Group 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT03960840
What this trial is testing

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaDiffuse Large B-cell Lymphoma+2 more
Novartis Pharmaceuticals 217
Testing effectiveness (Phase 2)Ended earlyNCT00361621
What this trial is testing

Ph II CHOP+Velcade in Mediastinal LBCL

Who this might be right for
Non-Hodgkin's Lymphoma
Dana-Farber Cancer Institute 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT05660967
What this trial is testing

Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Genmab 111
Not applicableUnknownNCT05800067
What this trial is testing

Axi-cel Retreatment in Relapsed/Refractory LBCL

Who this might be right for
CAR-T Retreatment
Ruijin Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT06905509
What this trial is testing

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements+11 more
Joseph Tuscano
Not applicableLooking for participantsNCT06830759
What this trial is testing

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Who this might be right for
Diffuse Large B-cell LymphomaFollicular Lymphoma
AbbVie 700
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