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Results for “Large B-cell Lymphoma (LBCL)”

46 trials

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Showing 20 of 46 results

Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Early research (Phase 1)Looking for participantsNCT07361224
What this trial is testing

Investigator Initiated Study to Assess the Safety of Combination of CLS-015 With Anti-CD-19 CAR-T Cells in Patients With Stable/Progressive Large B Cell Lymphoma at Lymphodepletion.

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Tel-Aviv Sourasky Medical Center 12
Testing effectiveness (Phase 2)Looking for participantsNCT06526793
What this trial is testing

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

Who this might be right for
B-cell Non-Hodgkin LymphomaFollicular Lymphoma (FL)Large B-Cell Lymphoma (LBCL)
AstraZeneca 240
Testing effectiveness (Phase 2)Looking for participantsNCT04844866
What this trial is testing

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Who this might be right for
Diffuse Large B-cell Lymphoma
Miltenyi Biomedicine GmbH 213
Testing effectiveness (Phase 2)Looking for participantsNCT06287398
What this trial is testing

Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL

Who this might be right for
DLBCL - Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaHigh Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements+4 more
Australasian Leukaemia and Lymphoma Group 39
Not applicableLooking for participantsNCT07524816
What this trial is testing

Real World Practice With Academic Anti CD19 CAR-T Cell Therapy in Relapse/Refractory B-cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
N.N. Alexandrov National Cancer Centre 76
Testing effectiveness (Phase 2)Active Not RecruitingNCT05660967
What this trial is testing

Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Genmab 111
Testing effectiveness (Phase 2)Looking for participantsNCT06905509
What this trial is testing

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements+11 more
Joseph Tuscano
Testing effectiveness (Phase 2)Looking for participantsNCT06542250
What this trial is testing

Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

Who this might be right for
B-cell Malignancies
AstraZeneca 174
Testing effectiveness (Phase 2)Active Not RecruitingNCT03960840
What this trial is testing

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaDiffuse Large B-cell Lymphoma+2 more
Novartis Pharmaceuticals 217
Testing effectiveness (Phase 2)Looking for participantsNCT06489808
What this trial is testing

Linperlisib Combined With Immunochemotherapy in Relapsed/Refractory LBCL

Who this might be right for
Relapsed/Refractory Large B-Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China 89
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07447726
What this trial is testing

Exploratory Clinical Study on the Safety and Efficacy of CD19X CAR-T Cell Injection in the Treatment of Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Institute of Hematology & Blood Diseases Hospital, China 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT07461831
What this trial is testing

CD19/ CD22 Bispecific CAR-T Cell Therapy for Relapsed/ Refractory Large B-cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Beijing Tongren Hospital 100
Testing effectiveness (Phase 2)Looking for participantsNCT06479356
What this trial is testing

CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaLarge B-cell Lymphoma
Shanghai Ming Ju Biotechnology Co., Ltd. 12
Large-scale testing (Phase 3)Active Not RecruitingNCT05605899
What this trial is testing

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

Who this might be right for
High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company 300
Testing effectiveness (Phase 2)Looking for participantsNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Not applicableUnknownNCT06142175
What this trial is testing

Relmacabtagene Autoleucel in Patients With LBCL

Who this might be right for
Large B-cell Lymphoma
Shanghai Ming Ju Biotechnology Co., Ltd. 200
Testing effectiveness (Phase 2)Looking for participantsNCT07514169
What this trial is testing

The Efficacy and Safety of Pola-ZR-Glo in Older Treatment-naive Patients With LBCL

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Ruijin Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT04661020
What this trial is testing

CD19 CAR-T Therapy for Patients With Newly Diagnosed High-risk Large B-cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
Zhejiang University 40
Testing effectiveness (Phase 2)Looking for participantsNCT07240194
What this trial is testing

The Efficacy and Safety of Glofitamab in Combination With PD-1 Antibody and Lenalidomide in Patients With Relapsed/Refractory Large B-cell Lymphoma (LBCL) With TP53 Aberrations: A Prospective, Multicenter, Phase II Clinical Study

Who this might be right for
Large B-cell LymphomaTP53
The First Affiliated Hospital with Nanjing Medical University 24
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