Not applicableStudy completedNCT02405182What this trial is testingMRI Biomarkers in ALSWho this might be right forAmyotrophic Lateral SclerosisALSMotor Neuron Diseases University of Alberta 145
Not applicableLooking for participantsNCT06318585What this trial is testingCreation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron DiseasesWho this might be right forAmyotrophic Lateral SclerosisMotor Neuron Disease Istituto Auxologico Italiano 200
Testing effectiveness (Phase 2)Study completedNCT01281631What this trial is testingNP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Neuraltus Pharmaceuticals, Inc. 136
Not applicableNo Longer AvailableNCT03537807What this trial is testingExpanded Access Protocol of BHV-0223 for Patients With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral SclerosisALSLou Gehrig Disease+3 more Biohaven Pharmaceuticals, Inc.
Not applicableActive Not RecruitingNCT04875416What this trial is testingPhenotype, Genotype and Biomarkers 2Who this might be right forAmyotrophic Lateral SclerosisHereditary Spastic ParaplegiaPrimary Lateral Sclerosis+2 more University of Miami 217
Not applicableStudy completedNCT05404867What this trial is testingStudy of Structural and Functional Brain Connectivity Changes in ALS (CoALS-II)Who this might be right forAmyotrophic Lateral Sclerosis Dartmouth-Hitchcock Medical Center 31
Not applicableLooking for participantsNCT06147843What this trial is testingFrench-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis University Hospital, Limoges 1,000
Not applicableLooking for participantsNCT06553976What this trial is testingSpastic Paraplegia - Centers of Excellence Research NetworkWho this might be right forHereditary Spastic ParaplegiaPrimary Lateral SclerosisSPG4+6 more Boston Children's Hospital 100
Testing effectiveness (Phase 2)Study completedNCT00214110What this trial is testingTamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS]Who this might be right forAmyotrophic Lateral Sclerosis (ALS) University of Wisconsin, Madison 100
Not applicableStudy completedNCT02360891What this trial is testingStudy of Predictive Factors of Progression of Motor Neurone DiseaseWho this might be right forAmyotrophic Lateral SclerosisMotor Neuron Disease University Hospital, Lille 500
Not applicableStudy completedNCT01699451What this trial is testingDNA, Blood and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic FloridaWho this might be right forAmyotrophic Lateral Sclerosis (ALS) Mayo Clinic 33
Early research (Phase 1)Study completedNCT01511029What this trial is testingStudy to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)Who this might be right forAmyotrophic Lateral Sclerosis Knopp Biosciences 68
Large-scale testing (Phase 3)Ended earlyNCT03948178What this trial is testingEffects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label ExtensionWho this might be right forAmyotrophic Lateral Sclerosis Orion Corporation, Orion Pharma 227
Not applicableStudy completedNCT03613038What this trial is testingA Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive DysarthriaWho this might be right forAmyotrophic Lateral SclerosisParkinson Disease University of Missouri-Columbia 100
Testing effectiveness (Phase 2)UnknownNCT04952155What this trial is testingLow Dose IL-2 in the Treatment of Immune-associated ALS SyndromeWho this might be right forAmyotrophic Lateral Sclerosis Peking University Third Hospital 13
Not applicableUnknownNCT05423678What this trial is testingClinical Trial - Analyzing Participation Experiences Of Amyotrophic Lateral Sclerosis PatientsWho this might be right forALSAmyotrophic Lateral Sclerosis Power Life Sciences Inc. 500
Testing effectiveness (Phase 2)Study completedNCT01786174What this trial is testingGilenya in Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Massachusetts General Hospital 30
Testing effectiveness (Phase 2)Study completedNCT00140218What this trial is testingR(+) Pramipexole in Early Amyotrophic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis Bennett, James P., Jr., M.D., Ph.D. 30
Testing effectiveness (Phase 2)Looking for participantsNCT07023835What this trial is testingUsnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis (ALS) Zydus Therapeutics Inc. 240
Post-approval studies (Phase 4)Study completedNCT01811355What this trial is testingMexiletine for the Treatment of Muscle Cramps in ALSWho this might be right forMuscle Cramps in Amyotrophic Lateral Sclerosis Bjorn Oskarsson, MD 23