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Results for “Leber Hereditary Optic Neuropathy (LHON)”

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Showing 20 of 0 results

Not applicableStudy completedNCT02796274
What this trial is testing

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 219
Large-scale testing (Phase 3)Active Not RecruitingNCT07406854
What this trial is testing

A Phase 3, Multicenter, Randomized, Double-Masked, Sham-Controlled Clinical Trial for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company 95
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
Large-scale testing (Phase 3)UnknownNCT03153293
What this trial is testing

A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
Huazhong University of Science and Technology 159
Not applicableLooking for participantsNCT03011541
What this trial is testing

Stem Cell Ophthalmology Treatment Study II

Who this might be right for
Retinal DiseaseAge-Related Macular DegenerationRetinitis Pigmentosa+15 more
MD Stem Cells 500
Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Early research (Phase 1)Not Yet RecruitingNCT07258667
What this trial is testing

Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)Leber's Hereditary Optic Neuropathy (LHON)Mitochondrial Disease+1 more
University Hospital, Angers 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT05293626
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 12
Post-approval studies (Phase 4)Study completedNCT02774005
What this trial is testing

Study to Assess the Efficacy and Safety of Raxone in LHON Patients

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 199
Not applicableNo Longer AvailableNCT03672968
What this trial is testing

EAP_GS010_single Patient

Who this might be right for
Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
GenSight Biologics
Testing effectiveness (Phase 2)Study completedNCT02023866
What this trial is testing

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease

Who this might be right for
Inherited Mitochondrial Disease, Including Leigh Syndrome
Amgen 36
Large-scale testing (Phase 3)WithdrawnNCT01495715
What this trial is testing

Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT04561466
What this trial is testing

Trial of Befizal® 200 mg for the Treatment of Leber Hereditary Optic Neuropathy

Who this might be right for
Safety IssuesEfficacy, Self
Hôpital Necker-Enfants Malades 14
Large-scale testing (Phase 3)Study completedNCT02652780
What this trial is testing

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 37
Not applicableNo Longer AvailableNCT02300753
What this trial is testing

Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON]

Who this might be right for
Leber's Hereditary Optic Neuropathy
Edison Pharmaceuticals Inc
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06792500
What this trial is testing

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

Who this might be right for
MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University 24
Large-scale testing (Phase 3)Study completedNCT00528151
What this trial is testing

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Optic Atrophy, Hereditary, Leber
Mahidol University 70
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
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