Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Leptin Receptor Deficiency Obesity”

4 trials

Showing 4 of 4 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07220772
What this trial is testing

A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults

Who this might be right for
Monogenic Obesity
Regeneron Pharmaceuticals 4
Not applicableAvailableNCT04710056
What this trial is testing

Expanded Access to REGN4461 for Patients With Lipodystrophy or Monogenic Obesity With Complications of Leptin Deficiency or Deficient Leptin Signaling

Who this might be right for
Lipodystrophy
Regeneron Pharmaceuticals
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
Large-scale testing (Phase 3)Study completedNCT03287960
What this trial is testing

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Who this might be right for
Leptin Receptor Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 15

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation