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Results for “Leptomeningeal Disease”

167 trials

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Showing 20 of 167 results

Early research (Phase 1)Looking for participantsNCT05184816
What this trial is testing

Deferoxamine (DFO) in People With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 35
Testing effectiveness (Phase 2)Ended earlyNCT03091478
What this trial is testing

Pembrolizumab in Patients With Leptomeningeal Disease

Who this might be right for
Patients With Leptomeningeal Disease
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 13
Early research (Phase 1)Not Yet RecruitingNCT07390539
What this trial is testing

B7-H3.CD28Z.CART in CNS Neoplasms

Who this might be right for
Central Nervous System NeoplasmsBrain TumorBrain Tumor, Recurrent+11 more
Robbie Majzner 70
Testing effectiveness (Phase 2)UnknownNCT01818713
What this trial is testing

Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 6
Post-approval studies (Phase 4)UnknownNCT04356118
What this trial is testing

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Hui Bu 30
Not applicableUnknownNCT00938756
What this trial is testing

Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerMetastatic Cancer
Centre Oscar Lambret 80
Testing effectiveness (Phase 2)Ended earlyNCT00830245
What this trial is testing

Assess the Efficacy of Erlotinib for Leptomeningeal Carcinomatosis in EGFR Mutation Positive Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal CarcinomatosisNon-small Cell Lung Cancer
Clinical Research Center for Solid Tumor, Korea 20
Testing effectiveness (Phase 2)Study completedNCT03507244
What this trial is testing

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 34
Not applicableStudy completedNCT02948751
What this trial is testing

Microfluidic Device to Diagnose Leptomeningeal Metastasis in Breast Cancer

Who this might be right for
Breast CancerLeptomeningeal Metastasis
Columbia University 14
Early research (Phase 1)Active Not RecruitingNCT03025256
What this trial is testing

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Who this might be right for
Acral Lentiginous MelanomaCentral Nervous System MelanomaClinical Stage IV Cutaneous Melanoma AJCC v8+7 more
M.D. Anderson Cancer Center 71
Testing effectiveness (Phase 2)Looking for participantsNCT06296745
What this trial is testing

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Not applicableLooking for participantsNCT06718972
What this trial is testing

A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China

Who this might be right for
Meningeal MetastasisNon-Small Cell Lung Cancer
Guangzhou Medical University 1,000
Post-approval studies (Phase 4)Looking for participantsNCT06230055
What this trial is testing

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
HER2-negative Breast CancerLeptomeningeal Metastasis
Fudan University 37
Testing effectiveness (Phase 2)Study completedNCT04233021
What this trial is testing

Study of Osimertinib in Patients with a Lung Cancer with Brain or Leptomeningeal Metastases with EGFR Mutation

Who this might be right for
Non Small Cell Lung Cancer MetastaticLeptomeningeal MetastasisBrain Metastases+1 more
Intergroupe Francophone de Cancerologie Thoracique 57
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Early research (Phase 1)Active Not RecruitingNCT04661384
What this trial is testing

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

Who this might be right for
EpendymomaGlioblastomaMedulloblastoma+1 more
City of Hope Medical Center 10
Not applicableNot Yet RecruitingNCT06766591
What this trial is testing

Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs

Who this might be right for
NSCLCChemotherapyLeptomeningeal Metastases+2 more
Jiangsu Province Nanjing Brain Hospital 36
Not applicableEnded earlyNCT05414123
What this trial is testing

A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseLeptomeningeal Neoplasms+2 more
Biocept, Inc. 40
Testing effectiveness (Phase 2)Study completedNCT00992602
What this trial is testing

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Who this might be right for
Central Nervous System MetastasesLeptomeningeal MetastasesRecurrent Breast Cancer+2 more
University of Washington 3
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