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Results for “Leptomeningeal Metastases”

178 trials

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Showing 20 of 178 results

Very early researchUnknownNCT05459441
What this trial is testing

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

Who this might be right for
GliomaBrain Metastases
Shanghai Pudong Hospital 30
Not applicableLooking for participantsNCT05746325
What this trial is testing

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Leptomeninges+2 more
Mayo Clinic 5
Testing effectiveness (Phase 2)UnknownNCT06339242
What this trial is testing

Furmonertinib Combined With Chemotherapy in the Treatment of NSCLC With Leptomeningeal Metastasis

Who this might be right for
NSCLC
Jiangsu Province Nanjing Brain Hospital 30
Early research (Phase 1)Looking for participantsNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 180
Testing effectiveness (Phase 2)Study completedNCT02616393
What this trial is testing

Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases

Who this might be right for
Non-Small Cell Lung CancerLeptomeningeal MetastasesBrain Metastases
Kadmon Corporation, LLC 36
Testing effectiveness (Phase 2)Study completedNCT01281696
What this trial is testing

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

Who this might be right for
Breast NeoplasmsLeptomeningeal MetastasisBrain Metastases
National Taiwan University Hospital 40
Not applicableUnknownNCT04778800
What this trial is testing

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

Who this might be right for
NSCLCBrain MetastasesLeptomeningeal Metastasis
Henan Cancer Hospital 60
Testing effectiveness (Phase 2)Study completedNCT00445965
What this trial is testing

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsIntraocular MelanomaLung Cancer+7 more
Memorial Sloan Kettering Cancer Center 78
Testing effectiveness (Phase 2)UnknownNCT01818713
What this trial is testing

Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 6
Not applicableActive Not RecruitingNCT05793489
What this trial is testing

Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin

Who this might be right for
Brain Metastases, Adult
Istituto Clinico Humanitas 44
Testing effectiveness (Phase 2)Looking for participantsNCT06518057
What this trial is testing

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
University of Washington 22
Early research (Phase 1)Study completedNCT02228369
What this trial is testing

Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer

Who this might be right for
EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
AstraZeneca 108
Testing effectiveness (Phase 2)Looking for participantsNCT06910761
What this trial is testing

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
City of Hope Medical Center 35
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Early research (Phase 1)Study completedNCT03520504
What this trial is testing

Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 24
Not applicableStudy completedNCT01713699
What this trial is testing

Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 146
Testing effectiveness (Phase 2)Looking for participantsNCT07193654
What this trial is testing

Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread

Who this might be right for
Glioblastoma (GBM)
Second Affiliated Hospital, School of Medicine, Zhejiang University 38
Testing effectiveness (Phase 2)Study completedNCT05146219
What this trial is testing

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

Who this might be right for
NSCLCEGFR Activating MutationBrain Metastases+1 more
TYK Medicines, Inc 29
Testing effectiveness (Phase 2)Looking for participantsNCT07304739
What this trial is testing

Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases

Who this might be right for
Non Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Post-approval studies (Phase 4)Looking for participantsNCT06230055
What this trial is testing

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
HER2-negative Breast CancerLeptomeningeal Metastasis
Fudan University 37
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