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Results for “Leptomeningeal Metastases”

190 trials

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Showing 20 of 190 results

Not applicableStudy completedNCT02948751
What this trial is testing

Microfluidic Device to Diagnose Leptomeningeal Metastasis in Breast Cancer

Who this might be right for
Breast CancerLeptomeningeal Metastasis
Columbia University 14
Testing effectiveness (Phase 2)Looking for participantsNCT06543992
What this trial is testing

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 22
Testing effectiveness (Phase 2)Study completedNCT06376292
What this trial is testing

A Prospective Single Arm Phase II Exploratory Study on the Combination of Whole Brain Radiotherapy, Thiotepa Intrathecal Injection and Systemic Treatment of Primary Diseases in the Treatment of Solid Tumor Leptomeningeal Metastasis

Who this might be right for
Solid Tumor Leptomeningeal Metastasis
Second Affiliated Hospital, Zhejiang University, School of Medicine 58
Not applicableUnknownNCT00938756
What this trial is testing

Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerMetastatic Cancer
Centre Oscar Lambret 80
Early research (Phase 1)Ended earlyNCT03661424
What this trial is testing

BATs in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Breast Cancer FemaleLeptomeningeal Metastases
University of Virginia 3
Not applicableLooking for participantsNCT06304441
What this trial is testing

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 100
Early research (Phase 1)Ended earlyNCT00527410
What this trial is testing

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

Who this might be right for
Leptomeningeal Carcinomatosis
Biogen 9
Testing effectiveness (Phase 2)Ended earlyNCT03501979
What this trial is testing

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

Who this might be right for
Metastatic Breast CancerLeptomeningeal Disease
University of Alabama at Birmingham 17
Early research (Phase 1)Active Not RecruitingNCT06724926
What this trial is testing

Concurrent Azeliragon With Craniospinal Irradiation

Who this might be right for
Solid TumorHigh-grade GliomaLeptomeningeal Metastasis
NYU Langone Health 21
Post-approval studies (Phase 4)UnknownNCT04356118
What this trial is testing

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Hui Bu 30
Not applicableLooking for participantsNCT06417710
What this trial is testing

Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseLeptomeningeal Neoplasms+1 more
University of Zurich 200
Testing effectiveness (Phase 2)Looking for participantsNCT06910761
What this trial is testing

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
City of Hope Medical Center 35
Not applicableLooking for participantsNCT06933199
What this trial is testing

Neoadjuvant Stereotactic Radiotherapy for Brain Metastasis

Who this might be right for
Brain Metastases
University Hospital Ostrava 260
Early research (Phase 1)Looking for participantsNCT06663306
What this trial is testing

Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC

Who this might be right for
Lung Cancer (NSCLC)Leptomeningeal Metastasis
Shanghai Chest Hospital 19
Large-scale testing (Phase 3)Study completedNCT01645839
What this trial is testing

Interest of Intrathecal Chemotherapy With Liposomal Cytarabine (DepoCyte®) in Meningeal Metastasis of Breast Cancer

Who this might be right for
Breast CancerLeptomeningeal Metastases
Centre Oscar Lambret 74
Testing effectiveness (Phase 2)Study completedNCT01373710
What this trial is testing

Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis

Who this might be right for
Metastatic Breast CancerCarcinomatous Meningitis
Institut Curie 34
Early research (Phase 1)UnknownNCT00003073
What this trial is testing

Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Pacira Pharmaceuticals, Inc 15
Testing effectiveness (Phase 2)Ended earlyNCT01596127
What this trial is testing

Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

Who this might be right for
LeukemiaLymphoid MalignanciesMetastatic Malignant Neoplasm to the Leptomeninges
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT07744529
What this trial is testing

Amivantamab Combined With Intrathecal Pemetrexed for LM From EGFR-Mutated Lung Adenocarcinoma

Who this might be right for
Leptomeningeal Metastasis From Lung Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 15
Not applicableNot Yet RecruitingNCT07704034
What this trial is testing

Wearable-Triggered Digital Safety Net for Real-Time Monitoring & Intervention in Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Case Comprehensive Cancer Center 48
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