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Results for “Leptomeningeal Metastasis From Lung Cancer”

15 trials

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Showing 15 of 15 results

Not applicableLooking for participantsNCT06304441
What this trial is testing

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 100
Testing effectiveness (Phase 2)Looking for participantsNCT07744529
What this trial is testing

Amivantamab Combined With Intrathecal Pemetrexed for LM From EGFR-Mutated Lung Adenocarcinoma

Who this might be right for
Leptomeningeal Metastasis From Lung Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 15
Not applicableNot Yet RecruitingNCT07689721
What this trial is testing

CtDNA-Guided Intraventricular Therapy for CNS Malignancies

Who this might be right for
Leptomeningeal DiseaseGlioblastomaBrain Metastases+2 more
Alireza Mansouri 77
Testing effectiveness (Phase 2)UnknownNCT04833205
What this trial is testing

Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Hui Bu 30
Testing effectiveness (Phase 2)Looking for participantsNCT07559097
What this trial is testing

Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer

Who this might be right for
Leptomeningeal Metastasis From Lung Cancer
Henan Cancer Hospital 14
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07789912
What this trial is testing

BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies

Who this might be right for
Leptomeningeal MetastasisBreast CancerLung Cancer (NSCLC)
University of Miami 40
Early research (Phase 1)Study completedNCT03101579
What this trial is testing

Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal Metastases
The First Hospital of Jilin University 13
Not applicableUnknownNCT03029065
What this trial is testing

Detection of CSF Next Generation Sequencing in the Application of Brain Metastases From Lung Adenocarcinoma or Meningeal Metastasis

Who this might be right for
Recruitment
Shandong Cancer Hospital and Institute 50
Testing effectiveness (Phase 2)UnknownNCT04425681
What this trial is testing

Osimertinib With Bevacizumab for Leptomeningeal Metastasis From EGFR-mutation Non-Small Cell Lung Cancer

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung CancerEGFR Activating Mutation
Second Affiliated Hospital of Nanchang University 20
Early research (Phase 1)Not Yet RecruitingNCT07702305
What this trial is testing

Safety and Efficacy of Intrathecal Sacituzumab Tirumotecan for Leptomeningeal Metastasis in EGFR-TKI-Resistant Non-Small Cell Lung Cancer

Who this might be right for
EGFR-TKI-resistant Non-small Cell Lung Cancer With Leptomeningeal Metastasis
Henan Cancer Hospital 15
Testing effectiveness (Phase 2)Looking for participantsNCT06518057
What this trial is testing

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
University of Washington 22
Testing effectiveness (Phase 2)Looking for participantsNCT06296745
What this trial is testing

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Not applicableLooking for participantsNCT07751536
What this trial is testing

CtDNA-driven Adaptive Proton Craniospinal Irradiation in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis After Resistance to Third-Generation TKIs in the Consolidation Phase

Who this might be right for
Leptomeningeal Metastasis From Lung Cancer
Shuanghu Yuan 84
Testing effectiveness (Phase 2)Study completedNCT05865990
What this trial is testing

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease

Who this might be right for
Metastatic Breast CancerAdvanced Non-Small Cell Squamous Lung CancerSolid Tumor, Adult
MedSIR 63
Testing effectiveness (Phase 2)UnknownNCT05810350
What this trial is testing

Aumolertinib Combined Intrathecal Chemotherapy for Leptomeningeal Metastasis From EGFR-Mutated NSCLC and Prognostic Value of Dynamic Changes in cfDNA Profiles

Who this might be right for
Non-small Cell Lung Cancer
Three Gorges Hospital of Chongqing University 40