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Results for “Leptomeningeal Metastasis in Breast Cancer”

40 trials

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Showing 20 of 40 results

Testing effectiveness (Phase 2)Looking for participantsNCT07134153
What this trial is testing

Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases

Who this might be right for
Breast Cancer
Fudan University 139
Testing effectiveness (Phase 2)UnknownNCT01818713
What this trial is testing

Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 6
Testing effectiveness (Phase 2)Looking for participantsNCT06543992
What this trial is testing

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 22
Testing effectiveness (Phase 2)Looking for participantsNCT06810804
What this trial is testing

A Phase IIa Study to Evaluate NBQ72S

Who this might be right for
Breast Cancer
Nantong Bencao Quadriga Medical Technology Co. Ltd. 10
Testing effectiveness (Phase 2)Study completedNCT05865990
What this trial is testing

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease

Who this might be right for
Metastatic Breast CancerAdvanced Non-Small Cell Squamous Lung CancerSolid Tumor, Adult
MedSIR 63
Testing effectiveness (Phase 2)Looking for participantsNCT05800275
What this trial is testing

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseHER2-positive Metastatic Breast Cancer
UNICANCER 30
Large-scale testing (Phase 3)UnknownNCT03613181
What this trial is testing

ANG1005 in Leptomeningeal Disease From Breast Cancer

Who this might be right for
Leptomeningeal CarcinomatosisLeptomeningeal MetastasesBrain Metastases+1 more
Angiochem Inc 150
Not applicableNot Yet RecruitingNCT07659652
What this trial is testing

Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Who this might be right for
Breast Cancer, Quality of LifeBreast Cancer, MetastaticBreast Cancer, Metastatic Breast Cancer+2 more
University of California, San Francisco 200
Testing effectiveness (Phase 2)Study completedNCT01325207
What this trial is testing

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

Who this might be right for
Breast Cancer
Northwestern University 34
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Not applicableLooking for participantsNCT06638294
What this trial is testing

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30
Not applicableStudy completedNCT02948751
What this trial is testing

Microfluidic Device to Diagnose Leptomeningeal Metastasis in Breast Cancer

Who this might be right for
Breast CancerLeptomeningeal Metastasis
Columbia University 14
Not applicableNot Yet RecruitingNCT07689721
What this trial is testing

CtDNA-Guided Intraventricular Therapy for CNS Malignancies

Who this might be right for
Leptomeningeal DiseaseGlioblastomaBrain Metastases+2 more
Alireza Mansouri 77
Testing effectiveness (Phase 2)Looking for participantsNCT07263425
What this trial is testing

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of HER2-positive Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 26
Early research (Phase 1)Ended earlyNCT03661424
What this trial is testing

BATs in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Breast Cancer FemaleLeptomeningeal Metastases
University of Virginia 3
Not applicableWithdrawnNCT03974204
What this trial is testing

Analyses of Exosomes in the Cerebrospinal Fluid for Breast Cancer Patients With Suspicion of Leptomeningeal Metastasis.

Who this might be right for
Breast CancerLeptomeningeal Metastasis
Centre Oscar Lambret
Testing effectiveness (Phase 2)Ended earlyNCT03501979
What this trial is testing

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

Who this might be right for
Metastatic Breast CancerLeptomeningeal Disease
University of Alabama at Birmingham 17
Testing effectiveness (Phase 2)Study completedNCT00992602
What this trial is testing

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Who this might be right for
Central Nervous System MetastasesLeptomeningeal MetastasesRecurrent Breast Cancer+2 more
University of Washington 3
Early research (Phase 1)WithdrawnNCT06137651
What this trial is testing

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Who this might be right for
Breast CarcinomaMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges
Northwestern University
Large-scale testing (Phase 3)Looking for participantsNCT06500481
What this trial is testing

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
NRG Oncology 115
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