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Results for “Leptomeningeal Metastasis of HER2-positive Breast Cancer”

9 trials

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Showing 9 of 9 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07177950
What this trial is testing

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

Who this might be right for
Breast CancerBrain MetastasesLeptomeningeal Metastasis
Peking University Cancer Hospital & Institute 51
Testing effectiveness (Phase 2)Looking for participantsNCT05800275
What this trial is testing

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseHER2-positive Metastatic Breast Cancer
UNICANCER 30
Testing effectiveness (Phase 2)Study completedNCT04420598
What this trial is testing

DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease

Who this might be right for
Advanced Breast CancerHER2-positive Breast CancerBrain Metastases+1 more
MedSIR 41
Testing effectiveness (Phase 2)Looking for participantsNCT07263425
What this trial is testing

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of HER2-positive Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 26
Testing effectiveness (Phase 2)Study completedNCT01325207
What this trial is testing

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

Who this might be right for
Breast Cancer
Northwestern University 34
Early research (Phase 1)Active Not RecruitingNCT03696030
What this trial is testing

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Who this might be right for
Malignant NeoplasmMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges+2 more
City of Hope Medical Center 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04588545
What this trial is testing

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

Who this might be right for
HER2-positive Breast CancerLeptomeningeal MetastasisLeptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute 33
Testing effectiveness (Phase 2)Study completedNCT01373710
What this trial is testing

Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis

Who this might be right for
Metastatic Breast CancerCarcinomatous Meningitis
Institut Curie 34
Testing effectiveness (Phase 2)Ended earlyNCT03501979
What this trial is testing

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

Who this might be right for
Metastatic Breast CancerLeptomeningeal Disease
University of Alabama at Birmingham 17