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Results for “Leukodystrophies”

87 trials

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Showing 20 of 87 results

Not applicableUnknownNCT04319796
What this trial is testing

European Registry on Rare Neurological Diseases

Who this might be right for
Rare Diseases
University Hospital Tuebingen 5,000
Not applicableUnknownNCT04324775
What this trial is testing

Comparison of Acute Effect of Different Manual Techniques on Muscle Fascia Stiffness

Who this might be right for
Manual Lymphatic DrainageSwedish MassageMuscle Fascia Stiffness
Marmara University 30
Testing effectiveness (Phase 2)Study completedNCT01043640
What this trial is testing

Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders

Who this might be right for
MucopolysaccharidosisHurler SyndromeHunter Syndrome+10 more
Masonic Cancer Center, University of Minnesota 46
Not applicableWithdrawnNCT05755568
What this trial is testing

Learn About Metachromatic Leukodystrophy (MLD) in Children in Spain

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Takeda
Not applicableAvailableNCT07487389
What this trial is testing

Zilganersen Expanded Access Program for Individuals With Alexander Disease

Who this might be right for
Alexander Disease
Ionis Pharmaceuticals, Inc.
Not applicableStudy completedNCT02843555
What this trial is testing

Natural History of the Leukodystrophies

Who this might be right for
Leukodystrophies
Baylor Research Institute 10
Testing effectiveness (Phase 2)Study completedNCT01560182
What this trial is testing

Gene Therapy for Metachromatic Leukodystrophy (MLD)

Who this might be right for
Lysosomal Storage DiseaseMetachromatic Leukodystrophy
Orchard Therapeutics 20
Early research (Phase 1)WithdrawnNCT01003912
What this trial is testing

Fetal Umbilical Cord Blood (UCB) Transplant for Lysosomal Storage Diseases

Who this might be right for
Lysosomal Storage DiseasesInborn Errors of Metabolism
Joanne Kurtzberg, MD
Not applicableStudy completedNCT01938014
What this trial is testing

Lysosomal Storage Disease: Health, Development, and Functional Outcome Surveillance in Preschool Children

Who this might be right for
Mucopolysaccharidosis Type I (MPS I)Mucopolysaccharidosis Type II (MPS II)Mucopolysaccharidosis Type III (MPS III)+2 more
University of Chicago 19
Not applicableStudy completedNCT00889174
What this trial is testing

The Nosology and Etiology of Leukodystrophies of Unknown Causes

Who this might be right for
LeukodystrophyLeukoencephalopathy
National Human Genome Research Institute (NHGRI) 76
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06369974
What this trial is testing

Single Participant Study of an Experimental ASO Treatment for TUBB4A-related Leukodystrophy

Who this might be right for
Genetic Disease
Massachusetts General Hospital 1
Testing effectiveness (Phase 2)Study completedNCT01510028
What this trial is testing

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD)

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Shire 24
Testing effectiveness (Phase 2)Study completedNCT01801709
What this trial is testing

Intracerebral Gene Therapy for Children With Early Onset Forms of Metachromatic Leukodystrophy

Who this might be right for
Metachromatic Leukodystrophy
Institut National de la Santé Et de la Recherche Médicale, France 5
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05739643
What this trial is testing

Gene Transfer Clinical Trial for Infantile and Late Infantile Krabbe Disease Treated Previously With HSCT

Who this might be right for
Krabbe Disease
Forge Biologics, Inc 9
Large-scale testing (Phase 3)Ended earlyNCT00654433
What this trial is testing

ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases

Who this might be right for
Inherited Metabolic DiseasesLysosomal Storage DisordersPeroxisomal Storage Diseases+2 more
Aldagen 40
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Not applicableNo Longer AvailableNCT02084121
What this trial is testing

Allogeneic Stem Cell Transplantation for the Treatment of Multiple Sclerosis (Compassionate Use)

Who this might be right for
Metachromatic Leukodystrophy
Talaris Therapeutics Inc.
Early research (Phase 1)Study completedNCT00418561
What this trial is testing

Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Shire 13
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