Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Leukoencephalopathy, Progressive Multifocal”

32 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 32 results

Very early researchStudy completedNCT04781309
What this trial is testing

NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy

Who this might be right for
Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS) 12
Large-scale testing (Phase 3)Not Yet RecruitingNCT06276504
What this trial is testing

Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Assistance Publique - Hôpitaux de Paris 33
Not applicableStudy completedNCT03969550
What this trial is testing

Do CCR5 Antagonists Improve the Overall Survival of Patients With AIDS-related Progressive Multifocal Leucoencephalopathy?

Who this might be right for
AIDSProgressive Multifocal Leucoencephalopathy (PML)
Fondation Ophtalmologique Adolphe de Rothschild 34
Not applicableStudy completedNCT04453917
What this trial is testing

Dynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal Leukoencephalopathy

Who this might be right for
Progressive Multifocal Leukoencephalopathy
University Hospital, Toulouse 22
Not applicableLooking for participantsNCT07732907
What this trial is testing

Risk of Progressive Multifocal Leukoencephalopathy Among Patients With Multiple Sclerosis Exposed to Zeposia

Who this might be right for
Multiple SclerosisProgressive Multifocal Leukoencephalopathy
Bristol-Myers Squibb 15
Testing effectiveness (Phase 2)Ended earlyNCT00746941
What this trial is testing

Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Biogen 37
Not applicableLooking for participantsNCT01730131
What this trial is testing

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Who this might be right for
Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS) 700
Testing effectiveness (Phase 2)Study completedNCT00002395
What this trial is testing

Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML)

Who this might be right for
HIV InfectionsLeukoencephalopathy, Progressive Multifocal
SmithKline Beecham 54
Not applicableStudy completedNCT01981161
What this trial is testing

Difference in Efficacy of Natalizumab Versus Fingolimod for the Treatment of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
University Hospital, Toulouse 307
Very early researchStudy completedNCT02694783
What this trial is testing

Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-Cells

Who this might be right for
Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS) 60
Testing effectiveness (Phase 2)Looking for participantsNCT06990087
What this trial is testing

T-cell Therapy in Patients With PML

Who this might be right for
Progressive Multifocal Leucoencephalopathy (PML)
Hannover Medical School 23
Not applicableStudy completedNCT06594614
What this trial is testing

Observational Study on Characteristics and Survival Correlates of Progressive Multifocal Leukoencephalopathy (PML) in Italy

Who this might be right for
Progressive Multifocal LeukoencephalopathyPML
Scientific Institute San Raffaele 456
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Post-approval studies (Phase 4)Study completedNCT01970410
What this trial is testing

MAIN STUDY: SWITCH SUB-STUDY: SWITCH-JCV

Who this might be right for
Multiple Sclerosis
Providence Health & Services 55
Not applicableStudy completedNCT00342602
What this trial is testing

Genetics of Progressive Multifocal Leukoencephalopathy and Acquired Immunodeficiency Syndrome

Who this might be right for
PMLAIDS
National Cancer Institute (NCI) 450
Post-approval studies (Phase 4)Ended earlyNCT01211665
What this trial is testing

Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)

Who this might be right for
Immune Reconstitution Inflammatory SyndromeLeukoencephalopathy, Progressive Multifocal
Biogen 3
Not applicableStudy completedNCT00000945
What this trial is testing

Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS Patients

Who this might be right for
HIV InfectionsLeukoencephalopathy, Progressive Multifocal
National Institute of Allergy and Infectious Diseases (NIAID) 24
Not applicableStudy completedNCT02895581
What this trial is testing

Retrospective Study of the Survival of Patients Suffering From Hiv-related Progressive Multifocal Leukoencephalopathy

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Fondation Ophtalmologique Adolphe de Rothschild 34
Not applicableLooking for participantsNCT07512518
What this trial is testing

Observational Cohort Study of Chronic Viral Infection in the Central Nervous System

Who this might be right for
Progressive Multifocal LeukoencephalopathyImmune Checkpoint Inhibitors
Peking Union Medical College Hospital 66
Testing effectiveness (Phase 2)UnknownNCT05541549
What this trial is testing

Study Evaluating JCPyV-specific T Cell Therapy for PML

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Cellevolve Bio Inc 60
Next Page