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Results for “Lewy Bodies Disease”

508 trials

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Showing 20 of 508 results

Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Testing effectiveness (Phase 2)Study completedNCT00630500
What this trial is testing

Efficacy and Safety of Memantine for Parkinson's Disease Dementia (PDD) and Dementia With Lewy Bodies (DLB)

Who this might be right for
Dementia Associated With Parkinson's DiseaseDementia With Lewy Bodies
Helse Stavanger HF 75
Large-scale testing (Phase 3)Study completedNCT04776148
What this trial is testing

Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 563
Testing effectiveness (Phase 2)Study completedNCT03797326
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerOvarian Cancer+5 more
Merck Sharp & Dohme LLC 611
Not applicableStudy completedNCT02263937
What this trial is testing

Deep Brain Stimulation for Patients With Dementia With Lewy Bodies

Who this might be right for
Dementia With Lewy Bodies
University College, London 6
Large-scale testing (Phase 3)Study completedNCT01905657
What this trial is testing

Study of Two Doses of Pembrolizumab (MK-3475) Versus Docetaxel in Previously Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010)

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC 1,034
Not applicableLooking for participantsNCT06941012
What this trial is testing

Validation of α-synuclein Modifications in Parkinson's dIsoRder Evolution

Who this might be right for
Parkinson Disease (PD)
Casa di Cura IGEA 1,200
Not applicableActive Not RecruitingNCT03648905
What this trial is testing

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Who this might be right for
Parkinson's DiseaseMultiple System AtrophyAutonomic Failure
National Institute of Neurological Disorders and Stroke (NINDS) 89
Very early researchLooking for participantsNCT06098612
What this trial is testing

PET Imaging Evaluation of [11C]SY08

Who this might be right for
Parkinson's DiseaseMultiple System AtrophyDementia With Lewy Bodies+1 more
Massachusetts General Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT07147348
What this trial is testing

A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 375
Large-scale testing (Phase 3)Study completedNCT03635567
What this trial is testing

Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)

Who this might be right for
Cervical Cancer
Merck Sharp & Dohme LLC 617
Large-scale testing (Phase 3)Study completedNCT02564263
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)

Who this might be right for
Esophageal CarcinomaEsophagogastric Junction Carcinoma
Merck Sharp & Dohme LLC 628
Large-scale testing (Phase 3)Active Not RecruitingNCT04736706
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 1,653
Large-scale testing (Phase 3)Active Not RecruitingNCT03711032
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
Merck Sharp & Dohme LLC 1,397
Testing effectiveness (Phase 2)Active Not RecruitingNCT04305054
What this trial is testing

Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 315
Large-scale testing (Phase 3)Study completedNCT02864394
What this trial is testing

Study of Pembrolizumab Versus Docetaxel in Participants Previously Treated for Non-Small Cell Lung Cancer (MK-3475-033/KEYNOTE-033)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 425
Not applicableLooking for participantsNCT06120361
What this trial is testing

The Swedish BioFINDER - Primary Care Study

Who this might be right for
Mild DementiaMild Cognitive ImpairmentSCD+4 more
Skane University Hospital 1,200
Not applicableStudy completedNCT05052450
What this trial is testing

Factors Associated With Mortality, Morbidity and Prognosis in Dementia Patients

Who this might be right for
DementiaDementia, VascularDementia With Lewy Bodies+3 more
Gulhane Training and Research Hospital 1,000
Not applicableWithdrawnNCT01256905
What this trial is testing

Attention Modulation for Treatment of Parkinson's Disease and Dementia With Lewy Bodies

Who this might be right for
Parkinsons DiseaseLewy Bodies Disease
NYU Langone Health
Early research (Phase 1)Study completedNCT07105371
What this trial is testing

Patients With ALS and Other Motor Disorders Will be Treated With Mesenchymal Cell Exosome Solution

Who this might be right for
Motor Disorders
The Foundation for Orthopaedics and Regenerative Medicine 18
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