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Results for “Light Chain (AL) Amyloidosis”

162 trials

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Showing 20 of 162 results

Large-scale testing (Phase 3)Ended earlyNCT04973137
What this trial is testing

Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Prothena Biosciences Ltd. 208
Testing effectiveness (Phase 2)WithdrawnNCT05486481
What this trial is testing

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

Who this might be right for
AL AmyloidosisLight Chain (AL) AmyloidosisSystemic Light Chain Disease
Alfred Chung, MD
Testing effectiveness (Phase 2)UnknownNCT03252600
What this trial is testing

Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis

Who this might be right for
Recurrent Primary Amyloidosis
Barbara Ann Karmanos Cancer Institute 53
Not applicableStudy completedNCT04392960
What this trial is testing

Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis

Who this might be right for
AL Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 30
Early research (Phase 1)Ended earlyNCT00030381
What this trial is testing

Iododoxorubicin in Treating Patients With Primary Systemic Amyloidosis

Who this might be right for
Primary Systemic Amyloidosis
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Ended earlyNCT02613182
What this trial is testing

Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis

Who this might be right for
AL Amyloidosis
Prothena Biosciences Ltd. 34
Not applicableLooking for participantsNCT06365060
What this trial is testing

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

Who this might be right for
Smoldering Multiple Myeloma
Tufts Medical Center 400
Early research (Phase 1)Ended earlyNCT01807286
What this trial is testing

Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis

Who this might be right for
Myeloma
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Looking for participantsNCT06292780
What this trial is testing

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)

Who this might be right for
Relapsed/Refractory Systemic Light Chain Amyloidosis
Regeneron Pharmaceuticals 220
Not applicableLooking for participantsNCT01408225
What this trial is testing

Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource

Who this might be right for
Plasma Cell DyscrasiasMonoclonal Gammopathy of Undetermined SignificanceAL Amyloidosis+1 more
Ohio State University Comprehensive Cancer Center 5,000
Not applicableLooking for participantsNCT06894290
What this trial is testing

International Cardiac Amyloidosis Registry

Who this might be right for
Cardiac Amyloidosis
Leiden University Medical Center 300
Not applicableUnknownNCT05277493
What this trial is testing

A Registry of Chinese AL Amyloidosis Patients Treated With Subcutaneous or Intravenous Daratumumab

Who this might be right for
AL Amyloidosis
Peking Union Medical College Hospital 500
Not applicableLooking for participantsNCT06971848
What this trial is testing

Evaluation of Skin Tests in Biotherapy Allergies

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckMelanoma NeoplasmsSmall Cell Bronchial Carcinomas+13 more
University Hospital, Angers 70
Large-scale testing (Phase 3)Not Yet RecruitingNCT07793422
What this trial is testing

Study to Evaluate Change in Disease Activity and Adverse Events of Subcutaneous Etentamig Compared With Daratumumab Plus Cyclophosphamide Plus Bortezomib Plus Dexamethasone (Dara-CyBorD) in Adults With Amyloid Light Chain (AL) Amyloidosis

Who this might be right for
Amyloid Light Chain (AL) Amyloidosis
AbbVie 370
Large-scale testing (Phase 3)Ended earlyNCT02489500
What this trial is testing

Trial of High Dose Melphalan/Stem Cell Transplant With or Without Bortezomib

Who this might be right for
AL Amyloidosis
Boston Medical Center 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055724
What this trial is testing

Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis

Who this might be right for
AL Amyloidosis
Nanjing IASO Biotechnology Co., Ltd. 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT03618537
What this trial is testing

Ixazomib Maintenance Study in Patients With AL Amyloidosis

Who this might be right for
AL Amyloidosis
Memorial Sloan Kettering Cancer Center 17
Testing effectiveness (Phase 2)Study completedNCT01677286
What this trial is testing

Safety and Effect of Doxycycline in Patients With Amyloidosis

Who this might be right for
Amyloidosis
Boston University 25
Early research (Phase 1)Study completedNCT00807872
What this trial is testing

Radioimmunoimaging of AL Amyloidosis

Who this might be right for
Primary Amyloidosis
University of Tennessee 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT07709715
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of NXC-201 Compared With Daratumumab With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) in Newly Diagnosed Systemic AL Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Nexcella Inc. 260
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