Not applicableLooking for participantsNCT03553420What this trial is testingRegistry for Patients With LipodystrophyWho this might be right forLipodystrophy AcquiredLipodystrophy Congenital University of Ulm 5,000
Not applicableStudy completedNCT02858830What this trial is testingFamilial Partial Lipodystrophy StudyWho this might be right forLipodystrophy, Familial Partial Mayo Clinic 12
Not applicableStudy completedNCT04845165What this trial is testingStudy of Cortisol Metabolism in Familial Partial Lipodystrophy Type 2Who this might be right forFamilial Partial Lipodystrophy Type 2 University Hospital, Lille 25
Not applicableNot Yet RecruitingNCT07412028What this trial is testingIdentification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)Who this might be right forPolycystic Ovary SyndromeFamilial Partial LipodystrophyLMNA (LaMin Nuclear A) Related Disorders Assistance Publique - Hôpitaux de Paris 81
Not applicableStudy completedNCT05424913What this trial is testingExploratory Study of the Relationships Between the Biomarkers of Inflammation, Lipidome and Insulin Resistance and Disorders of Glycemic Regulation in a Cohort of Insulin-resistant Subjects Due to Excess Weight or Dunnigan's LipodystrophyWho this might be right forLipodystrophyDunnigan Syndrome Centre Hospitalier Universitaire de la Réunion 150
Not applicableUnknownNCT06107439What this trial is testingImpact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island SubjectsWho this might be right forLipodystrophyDunnigan Syndrome Centre Hospitalier Universitaire de la Réunion 80
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100What this trial is testingThe Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)Who this might be right forGeneralized Lipodystrophy Regeneron Pharmaceuticals 9
Not applicableWithdrawnNCT04056000What this trial is testingLipodystrophy and Fat Metabolism During ExerciseWho this might be right forHealthyLipodystrophy, Familial Partial University of Exeter
Large-scale testing (Phase 3)Looking for participantsNCT06679270What this trial is testingOpen-label Extension Study to Evaluate Metreleptin in Patients With Partial LipodystrophyWho this might be right forFamilial Partial Lipodystrophy Amryt Pharma 24
Testing effectiveness (Phase 2)Ended earlyNCT05088460What this trial is testingExamine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD)Who this might be right forFamilial Partial LipodystrophyMetabolic Abnormalities Regeneron Pharmaceuticals 20
Large-scale testing (Phase 3)Looking for participantsNCT07220785What this trial is testingEfficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized LipodystrophyWho this might be right forGeneralized Lipodystrophy Regeneron Pharmaceuticals 28
Not applicableStudy completedNCT02577952What this trial is testingLipodystrophy Connect Patient RegistryWho this might be right forLipodystrophy PatientCrossroads 257
Testing effectiveness (Phase 2)Study completedNCT02430077What this trial is testingPhase 2 Study of Obeticholic Acid for Lipodystrophy PatientsWho this might be right forFamilial Partial Lipodystrophy Abhimanyu Garg 10
Not applicableAvailableNCT02404896What this trial is testingExpanded Access Metreleptin StudyWho this might be right forFamilial Partial Lipodystrophy University of Michigan
Not applicableLooking for participantsNCT05996536What this trial is testingFeasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)Who this might be right forLipodystrophy National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 14
Testing effectiveness (Phase 2)Study completedNCT02654977What this trial is testingCLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial LipodystrophyWho this might be right forFamilial Partial LipodystrophyNonalcoholic SteatohepatitisNAFLD University of Michigan 11
Not applicableStudy completedNCT07090629What this trial is testingThe Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.Who this might be right forHigh CholesterolLipodystrophy, Familial PartialDiabetes Centre Hospitalier Universitaire de la Réunion 126
Large-scale testing (Phase 3)Ended earlyNCT02527343What this trial is testingThe BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial LipodystrophyWho this might be right forFamilial Partial Lipodystrophy Akcea Therapeutics 40
Not applicableLooking for participantsNCT05789251What this trial is testingAssess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)Who this might be right forLipodystrophy Centre Hospitalier Universitaire de la Réunion 60
Not applicableLooking for participantsNCT03900286What this trial is testingLow Energy Diet and Familial Partial LipodystrophyWho this might be right forLipodystrophyDiabetesDiet Modification Cambridge University Hospitals NHS Foundation Trust 20