Not applicableLooking for participantsNCT03553420What this trial is testingRegistry for Patients With LipodystrophyWho this might be right forLipodystrophy AcquiredLipodystrophy Congenital University of Ulm 5,000
Not applicableNot Yet RecruitingNCT06863441What this trial is testingThe Value of PET Imaging Targeting Granzyme B in Predicting Efficacy and Prognosis in T-NK Cell LymphomaWho this might be right forT-NK Cell Lymphoma Ruijin Hospital 50
Not applicableStudy completedNCT02858830What this trial is testingFamilial Partial Lipodystrophy StudyWho this might be right forLipodystrophy, Familial Partial Mayo Clinic 12
Not applicableStudy completedNCT04845165What this trial is testingStudy of Cortisol Metabolism in Familial Partial Lipodystrophy Type 2Who this might be right forFamilial Partial Lipodystrophy Type 2 University Hospital, Lille 25
Not applicableNot Yet RecruitingNCT07412028What this trial is testingIdentification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)Who this might be right forPolycystic Ovary SyndromeFamilial Partial LipodystrophyLMNA (LaMin Nuclear A) Related Disorders Assistance Publique - Hôpitaux de Paris 81
Large-scale testing (Phase 3)Study completedNCT00896298What this trial is testingTrial of Leptin Replacement Therapy in Patients With LipodystrophyWho this might be right forHypoleptinemiaGeneralized LipodystrophyPartial Lipodystrophy+1 more University of Texas Southwestern Medical Center 25
Large-scale testing (Phase 3)Active Not RecruitingNCT02262832What this trial is testingCompassionate Use of Metreleptin in Previously Treated People With Generalized LipodystrophyWho this might be right forLipodystrophyDiabetesHyperlipidemia National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 24
Not applicableStudy completedNCT05424913What this trial is testingExploratory Study of the Relationships Between the Biomarkers of Inflammation, Lipidome and Insulin Resistance and Disorders of Glycemic Regulation in a Cohort of Insulin-resistant Subjects Due to Excess Weight or Dunnigan's LipodystrophyWho this might be right forLipodystrophyDunnigan Syndrome Centre Hospitalier Universitaire de la Réunion 150
Testing effectiveness (Phase 2)Study completedNCT05000372What this trial is testing68Ga-grazytracer PET/CT of Tumor Responses to ImmunotherapyWho this might be right forCancer Peking University Cancer Hospital & Institute 24
Not applicableUnknownNCT00345280What this trial is testingOcular Surface Changes in Patients With Cystic FibrosisWho this might be right forEye Manifestations University of Bialystok 26
Not applicableStudy completedNCT02056912What this trial is testingIdentification of a New Gene Involved in Hereditary LipodystrophyWho this might be right forLipodystrophy University Hospital, Bordeaux 2
Not applicableStudy completedNCT06089759What this trial is testingPerformance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling TreatmentWho this might be right forLipodystrophyDeformities Aesthetic Group 108
Not applicableLooking for participantsNCT06755775What this trial is testingPET Imaging Targeting Granzyme B Predicts Immunotherapy Efficacy in Diffuse Large B-cell LymphomaWho this might be right forDiffuse Large B-Cell Lymphoma Ruijin Hospital 150
Not applicableLooking for participantsNCT02325674What this trial is testingMEASuRE: Metreleptin Effectiveness And Safety RegistryWho this might be right forGeneralised LipodystrophyPartial Lipodystrophy Amryt Pharma 100
Not applicableUnknownNCT06107439What this trial is testingImpact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island SubjectsWho this might be right forLipodystrophyDunnigan Syndrome Centre Hospitalier Universitaire de la Réunion 80
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100What this trial is testingThe Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)Who this might be right forGeneralized Lipodystrophy Regeneron Pharmaceuticals 9
Not applicableLooking for participantsNCT04808596What this trial is testingPulmonary Hypertension Biorepository and RegistryWho this might be right forPulmonary HypertensionPulmonary Arterial HypertensionPulmonary Hypertension Due to Left Heart Disease+6 more University of Kansas Medical Center 300
Post-approval studies (Phase 4)Study completedNCT03344159What this trial is testingSpironolactone Therapy in Chronic Stable Right HF TrialWho this might be right forChronic Right-Sided Heart FailurePulmonary Arterial HypertensionPulmonary Hypertension, Primary, 2+3 more Ottawa Heart Institute Research Corporation 15
Not applicableWithdrawnNCT04056000What this trial is testingLipodystrophy and Fat Metabolism During ExerciseWho this might be right forHealthyLipodystrophy, Familial Partial University of Exeter
Not applicableAvailableNCT04710056What this trial is testingExpanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin SignalingWho this might be right forLipodystrophyGeneralized Lipodystrophy (GLD)Monogenic Obesity (MOB) Regeneron Pharmaceuticals