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Results for “Liposomal Irinotecan”

196 trials

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Showing 20 of 196 results

Testing effectiveness (Phase 2)Looking for participantsNCT07559760
What this trial is testing

New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
The First Hospital of Jilin University 30
Not applicableUnknownNCT06443307
What this trial is testing

Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan

Who this might be right for
Colorectal CancerSolid Tumor
Peking University 933
Large-scale testing (Phase 3)Study completedNCT05074589
What this trial is testing

Irinotecan Liposome in Combination With 5-FU/LV Versus 5-FU/LV in Second-line Therapy for Gemcitabine-Refractory Pancreatic Cancer

Who this might be right for
Second-line Treatment for Locally Advanced or Metastatic Pancreatic Cancer After Treatment Failure With Gemcitabine-based Therapy
Jiangsu HengRui Medicine Co., Ltd. 298
Early research (Phase 1)Study completedNCT03883919
What this trial is testing

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Who this might be right for
Pancreatic CancerPancreas CancerCancer of the Pancreas
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06993025
What this trial is testing

Ivonescimab in Combination With Liposomal Irinotecan and 5-FU/LV in Potentially Resectable Biliary Tract Malignancies

Who this might be right for
Biliary Tract Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06577376
What this trial is testing

A PhaseⅠ/Ⅱ Study of Simmitinib or Irinotecan Liposomes Combined With DP303c in Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Localized Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction AdenocarcinomaExpressing Human Epidermal Growth Factor Receptor-2 (HER-2)Disease Progression After Receiving at Least One and at Most Two Lines of Systemic Treatment in the Past
Shanghai Runshi Pharmaceutical Technology Co., Ltd
Testing effectiveness (Phase 2)Looking for participantsNCT07831993
What this trial is testing

Sintilimab Plus NALIRIFOX or Gemcitabine-Cisplatin as First-Line Treatment for Metastatic Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 54
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06192680
What this trial is testing

Liposomal Irinotecan and Capecitabine Plus Bevacizumab as Second-line Therapy in Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Harbin Medical University 63
Testing effectiveness (Phase 2)UnknownNCT06430827
What this trial is testing

Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma

Who this might be right for
Biliary Tract Carcinoma
Ba Yi 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT07585279
What this trial is testing

A Clinical Study of Liposomal Irinotecan for Second-Line Therapy in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)Liposomal IrinotecanSecond-Line
Hebei Medical University Fourth Hospital 408
Early research (Phase 1)UnknownNCT06300489
What this trial is testing

Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Zhejiang Cancer Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04233866
What this trial is testing

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Who this might be right for
Metastatic Pancreatic AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
ECOG-ACRIN Cancer Research Group 176
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06820762
What this trial is testing

Irinotecan Liposome(II) Combined With Ivonescimab as Second-line Treatment for Small Cell Lung Cancer : A Prospective, Single-arm, Multicenter Clinical Study

Who this might be right for
SCLC
The Second Affiliated Hospital of Dalian Medical University 40
Early research (Phase 1)Study completedNCT00940758
What this trial is testing

Phase I and Pharmacokinetic Study of Biweekly PEP02 in mCRC Refractory to 1st-line Oxaliplatin Base Therapy

Who this might be right for
Metastatic Colorectal Cancer
PharmaEngine 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07524374
What this trial is testing

SHR-1701 in Combination With Irinotecan Liposome (II) for Second-line Treatment of ESCC After Immunotherapy

Who this might be right for
ESCC
Zhigang Li 33
Testing effectiveness (Phase 2)UnknownNCT05865925
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK), and Primary Clinical Efficacy of LY01616 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Luye Pharma Group Ltd. 78
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04901741
What this trial is testing

Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Cancer
TME Pharma AG 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07239622
What this trial is testing

Liposomal Irinotecan Combined With Sintilimab and Anlotinib in the Treatment of Recurrent or Persistent Ovarian Clear Cell Carcinoma

Who this might be right for
Ovarian CancerOvarian Clear Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 36
Testing effectiveness (Phase 2)Looking for participantsNCT07542002
What this trial is testing

Liposomal Irinotecan, 5-fluorouracil/Calcium Folinate, Oxaliplatin, and Adebrelimab in Combination With Radiotherapy for Resectable or Borderline Resectable Pancreatic Cancer With Risk Factors：A Prospective Exploratory Study

Who this might be right for
Pancreatic Cancer
Ningbo Medical Center Lihuili Hospital 37
Early research (Phase 1)Not Yet RecruitingNCT06491134
What this trial is testing

Liposomal Irinotecan With Cisplatin and Concurrent Radiotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 12
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