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Results for “Liver Cancer (Locally Advanced or Metastatic)”

79 trials

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Showing 20 of 79 results

Testing effectiveness (Phase 2)Ended earlyNCT05070247
What this trial is testing

TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Pancreatic CancerHepatocellular CancerMesothelioma+7 more
Takeda 61
Testing effectiveness (Phase 2)Looking for participantsNCT06349980
What this trial is testing

Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.

Who this might be right for
Carcinoma, Hepatocellular
Shanghai Henlius Biotech 117
Early research (Phase 1)Looking for participantsNCT07390838
What this trial is testing

SH009 Injection in Patients With Advanced Solid Tumors.

Who this might be right for
Liver Cancer (Locally Advanced or Metastatic)Lung Cancer (NSCLC)Head and Neck Cancer Squamous Cell Carcinoma+4 more
Nanjing Sanhome Pharmaceutical, Co., Ltd. 150
Early research (Phase 1)Active Not RecruitingNCT03821935
What this trial is testing

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 364
Testing effectiveness (Phase 2)Looking for participantsNCT07410676
What this trial is testing

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Who this might be right for
CancerSarcomaLeukaemia+12 more
Essen Biotech 83
Early research (Phase 1)Looking for participantsNCT05661461
What this trial is testing

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Who this might be right for
Tumor, SolidTumorAdvanced Solid Tumor
Aadi Bioscience, Inc. 28
Large-scale testing (Phase 3)Looking for participantsNCT05078047
What this trial is testing

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Who this might be right for
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck Cancer+12 more
UNICANCER 646
Testing effectiveness (Phase 2)Study completedNCT04194801
What this trial is testing

A Phase Ib/II Study of Fisogatinib(BLU-554) in Subjects With Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
CStone Pharmaceuticals 26
Testing effectiveness (Phase 2)Looking for participantsNCT07227012
What this trial is testing

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Who this might be right for
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4 more
Pfizer 138
Testing effectiveness (Phase 2)Study completedNCT02089633
What this trial is testing

Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC

Who this might be right for
Hepatocellular Carcinoma
Bio-Cancer Treatment International Limited 17
Testing effectiveness (Phase 2)Ended earlyNCT04260802
What this trial is testing

Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Who this might be right for
CancerNeoplasmsMetastatic Cancer+16 more
Ocellaris Pharma, Inc. 73
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Study completedNCT00095992
What this trial is testing

SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer

Who this might be right for
Liver Cancer
NCIC Clinical Trials Group 15
Not applicableNo Longer AvailableNCT04087876
What this trial is testing

Expanded Access Use of Derazantinib for Advanced Intrahepatic Cholangiocarcinoma (iCCA) With FGFR Genomic Alterations

Who this might be right for
Intrahepatic Cholangiocarcinoma
Basilea Pharmaceutica
Testing effectiveness (Phase 2)Active Not RecruitingNCT05822752
What this trial is testing

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
AbbVie 130
Early research (Phase 1)Study completedNCT01273493
What this trial is testing

A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction

Who this might be right for
Neoplasm MetastasesHepatic Insufficiency
Janssen Research & Development, LLC 15
Testing effectiveness (Phase 2)Ended earlyNCT00427973
What this trial is testing

AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer+1 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Looking for participantsNCT05168163
What this trial is testing

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Who this might be right for
Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+6 more
Academic and Community Cancer Research United 122
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05897138
What this trial is testing

Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Who this might be right for
Hepatocellular Carcinoma
Fujian Cancer Hospital 30
Testing effectiveness (Phase 2)Study completedNCT00867321
What this trial is testing

Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Liver Cancer
Alliance for Clinical Trials in Oncology 24
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