Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Local Advanced or Metastatic NSCLC”

21 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 21 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT06380348
What this trial is testing

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Who this might be right for
Local Advanced or Metastatic NSCLC
Shanghai JMT-Bio Inc. 398
Testing effectiveness (Phase 2)UnknownNCT05745740
What this trial is testing

RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation

Who this might be right for
Non-small Cell Lung Cancer
RemeGen Co., Ltd. 26
Large-scale testing (Phase 3)Ended earlyNCT02766140
What this trial is testing

SHR1020 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Squamous Non Small Cell Lung Cancer

Who this might be right for
Non Squamous Non Small Cell Lung
Jiangsu HengRui Medicine Co., Ltd. 12
Testing effectiveness (Phase 2)UnknownNCT04974879
What this trial is testing

Osimertinib Combined With Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Qingdao Central Hospital 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT05941897
What this trial is testing

Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy

Who this might be right for
Advanced or Metastatic NSCLC
AstraZeneca 39
Early research (Phase 1)Study completedNCT01155258
What this trial is testing

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more
University of Southern California 19
Testing effectiveness (Phase 2)UnknownNCT04872634
What this trial is testing

Evaluate the Safety and Anti-tumor Activity of SNK01 (NK Cells) Administered in Combination With Chemotherapy or Chemotherapy / Cetuximab in Local Advanced or Metastatic Non-small Cell Lung Cancer Patients Who Failed Tyrosine Kinase Inhibitor Treatment

Who this might be right for
Non-small Cell Lung Cancer
NKMAX Co., Ltd. 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07294261
What this trial is testing

Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLC

Who this might be right for
Local Advanced or Metastatic NSCLC
Sun Yat-sen University 69
Early research (Phase 1)Ended earlyNCT01282333
What this trial is testing

Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancer

Who this might be right for
Advanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver CancerMetastatic Transitional Cell Cancer of the Renal Pelvis and Ureter+11 more
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)Looking for participantsNCT04977453
What this trial is testing

GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Cancer+11 more
GI Innovation, Inc. 430
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06182761
What this trial is testing

Sunvozertinib Combined With Anlotinib in Local Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
NSCLC
Shanghai Zhongshan Hospital 45
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Not applicableEnded earlyNCT00087191
What this trial is testing

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

Who this might be right for
Advanced Adult Primary Liver CancerCarcinoma of the AppendixFallopian Tube Cancer+68 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05668988
What this trial is testing

DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)

Who this might be right for
Non-small Cell Lung Cancer
Dizal Pharmaceuticals 324
Early research (Phase 1)Looking for participantsNCT06427941
What this trial is testing

BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Hepatocellular CarcinomaLocal Advanced Hepatocellular CarcinomaAlpha-fetoprotein (AFP)-Producing Gastric Cancer+2 more
BeOne Medicines 140
Large-scale testing (Phase 3)Study completedNCT01038661
What this trial is testing

Tax First-line Chemotherapy With Different Doses and Then Maintenance Therapy

Who this might be right for
Lung Neoplasms
Sanofi 375
Testing effectiveness (Phase 2)Study completedNCT00016367
What this trial is testing

Cisplatin and Gemcitabine Plus Trastuzumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
M.D. Anderson Cancer Center 22
Large-scale testing (Phase 3)UnknownNCT05111197
What this trial is testing

Local Ablative Stereotactic Radiotherapy for Residual Hypermetabolic Lesion in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Long-term Responders to Immunotherapy

Who this might be right for
Locally Advanced Non Small Cell Lung CancerMetastatic Non Small Cell Lung Cancer
Institut Cancerologie de l'Ouest 112
Large-scale testing (Phase 3)Study completedNCT00478049
What this trial is testing

Iressa as Second Line Therapy in Advanced NSCLC-Asia

Who this might be right for
NSCLC
AstraZeneca 163
Testing effectiveness (Phase 2)Active Not RecruitingNCT06391944
What this trial is testing

JMT101 Combined With Osimertinib in Patients With Stage Ⅲb-Ⅳ Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Common Mutations

Who this might be right for
Local Advanced or Metastatic NSCLCHarboring EGFR Common Mutation
Shanghai JMT-Bio Inc. 161
Load More Results