Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced/ Metastatic NSCLC”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT06348927
What this trial is testing

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital 52
Not applicableUnknownNCT04208854
What this trial is testing

Observational Study With Metronomic Oral Vinorelbine in Elderly Patients With Locally Advanced / Metastatic Non-small-cell Lung Cancer (NSCLC)

Who this might be right for
Locally Advanced/ Metastatic NSCLC
International Group of Endovascular Oncology 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07294261
What this trial is testing

Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLC

Who this might be right for
Local Advanced or Metastatic NSCLC
Sun Yat-sen University 69
Post-approval studies (Phase 4)Study completedNCT01287754
What this trial is testing

Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Who Present EGFR Mutations

Who this might be right for
Non-Small Cell Lung Cancer
Hoffmann-La Roche 24
Large-scale testing (Phase 3)Study completedNCT03922997
What this trial is testing

Investigate the Safety and Efficacy of Atezolizumab in Previously-Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Hoffmann-La Roche 101
Not applicableActive Not RecruitingNCT03969823
What this trial is testing

Whole Genomic Landscape of Advanced EGFR-mutant NSCLC

Who this might be right for
Locally Advanced or Metastatic NSCLC
Seoul National University Hospital 148
Testing effectiveness (Phase 2)Looking for participantsNCT07486817
What this trial is testing

Beamion 44: A Study to Test How Well Zongertinib is Tolerated by People With Advanced Non-small Cell Lung Cancer With HER2 Mutations When Given in Combination With Chemotherapy With or Without Pembrolizumab

Who this might be right for
Lung Cancer, Non-squamous, Non-small Cell
Boehringer Ingelheim 60
Large-scale testing (Phase 3)UnknownNCT05673590
What this trial is testing

Utidelone Versus Docetaxel in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Beijing Biostar Pharmaceuticals Co., Ltd. 612
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Study completedNCT00702975
What this trial is testing

Study of Combination Therapy of Carboplatin -Gemcitabine Plus Bevacizumab Beyond Progression in Patients With Locally Advanced and/or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Not Received Prior Systemic Therapy

Who this might be right for
Locally Advanced Non-Small Cell Lung CancerNSCLC
Radboud University Medical Center 35
Testing effectiveness (Phase 2)Study completedNCT02289456
What this trial is testing

Phase II Safety and Tolerability Trial With Nab-Paclitaxel Plus Carboplatin Followed by Nab-Paclitaxel for First Line Treatment of NSCLC Subjects With ECOG PS 2

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Celgene 40
Testing effectiveness (Phase 2)Study completedNCT00256711
What this trial is testing

Phase II Iressa Versus Vinorelbine (INVITE)

Who this might be right for
Non-Small-Cell Lung Carcinoma
AstraZeneca 192
Testing effectiveness (Phase 2)Ended earlyNCT05091528
What this trial is testing

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more
Silverback Therapeutics 2
Not applicableStudy completedNCT03170284
What this trial is testing

Observational Study to Evalute the Efficacy and Safety of Avastin (Bevacizumab) in Addition to Platinum-Based Chemotherapy for First-Line Treatment of Participants With Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 150
Large-scale testing (Phase 3)Looking for participantsNCT06357533
What this trial is testing

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 675
Testing effectiveness (Phase 2)Ended earlyNCT01526928
What this trial is testing

Study to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) Patients

Who this might be right for
Locally Advanced or Metastatic Non Small Cell Lung Cancer
Clovis Oncology, Inc. 612
Testing effectiveness (Phase 2)Looking for participantsNCT06244771
What this trial is testing

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Who this might be right for
Advanced Solid Tumors With KRAS G12C MutationsSolid Tumor, AdultUnresectable Solid Tumor+5 more
Frontier Medicines Corporation 403
Large-scale testing (Phase 3)Active Not RecruitingNCT01933932
What this trial is testing

Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC

Who this might be right for
Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV
AstraZeneca 510
Testing effectiveness (Phase 2)Study completedNCT04143711
What this trial is testing

Study of DF1001 in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
Dragonfly Therapeutics 270
Early research (Phase 1)Study completedNCT04925284
What this trial is testing

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Who this might be right for
Non Small Cell Lung CancerCervical CancerSCCHN+8 more
Exelixis 269
Next Page