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Results for “Locally Advanced (Inoperable) or Metastatic Breast Cancer”

44 trials

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Showing 20 of 44 results

Large-scale testing (Phase 3)Looking for participantsNCT06767527
What this trial is testing

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer (TNBC)
Akeso 416
Large-scale testing (Phase 3)Study completedNCT03125902
What this trial is testing

Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Triple-Negative Breast Cancer
Hoffmann-La Roche 653
Testing effectiveness (Phase 2)Looking for participantsNCT04802759
What this trial is testing

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Who this might be right for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Hoffmann-La Roche 316
Large-scale testing (Phase 3)Active Not RecruitingNCT04305496
What this trial is testing

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Who this might be right for
Locally Advanced (Inoperable) or Metastatic Breast Cancer
AstraZeneca 818
Large-scale testing (Phase 3)Looking for participantsNCT06419621
What this trial is testing

PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic TNBC

Who this might be right for
Triple Negative Breast Cancer(TNBC)
Biotheus Inc. 360
Early research (Phase 1)Study completedNCT04925284
What this trial is testing

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Who this might be right for
Non Small Cell Lung CancerCervical CancerSCCHN+8 more
Exelixis 269
Large-scale testing (Phase 3)Looking for participantsNCT06926868
What this trial is testing

Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Who this might be right for
Breast Neoplasms
Bristol-Myers Squibb 500
Testing effectiveness (Phase 2)WithdrawnNCT03644589
What this trial is testing

Effect of Pembrolizumab and Cisplatin on Metastatic, Locally Recurrent or Inoperable Triple-Negative Breast Cancer

Who this might be right for
Estrogen Receptor NegativeHER2/Neu NegativeMetastatic Breast Cancer+3 more
University of Washington
Testing effectiveness (Phase 2)UnknownNCT05403333
What this trial is testing

Weekly Utidelone in HER2-negative Inoperable Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast NeoplasmsLocally Advanced or Metastatic Breast Cancer
Fudan University 61
Testing effectiveness (Phase 2)Study completedNCT02404844
What this trial is testing

Trial of BKM120/Tamoxifen-combination in Patients With HR-pos, HER2-neg Breast Cancer

Who this might be right for
Breast Cancer
University Hospital, Essen 48
Large-scale testing (Phase 3)Active Not RecruitingNCT06635447
What this trial is testing

Capivasertib+Fulvestrant asTreatment for Locally Advanced(Inoperable) or Metastatic HR+/HER2- Breast Cancer in Chinese Patients

Who this might be right for
Breast Cancer
AstraZeneca 258
Testing effectiveness (Phase 2)Looking for participantsNCT04115306
What this trial is testing

Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Phoenix Molecular Designs 61
Large-scale testing (Phase 3)Active Not RecruitingNCT05840211
What this trial is testing

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

Who this might be right for
Locally Advanced or Unresectable Metastatic Breast CancerStage IV Breast Cancer
Gilead Sciences 654
Testing effectiveness (Phase 2)Ended earlyNCT01495247
What this trial is testing

Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Inoperable Locally Advanced Breast CancerMetastatic Breast Cancer (MBC)
Novartis Pharmaceuticals 18
Early research (Phase 1)Active Not RecruitingNCT03845166
What this trial is testing

XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors

Who this might be right for
Neoplasm MalignantRenal Cell CarcinomaHormone Receptor Positive Breast Carcinoma+2 more
Exelixis 325
Not applicableStudy completedNCT01777958
What this trial is testing

HELENA Study: An Observational Study of Perjeta (Pertuzumab) in First-Line Treatment in Patients With Her2-Positive Advanced Breast Cancer After Adjuvant Herceptin Therapy

Who this might be right for
Breast Cancer
Hoffmann-La Roche 135
Testing effectiveness (Phase 2)Looking for participantsNCT06434064
What this trial is testing

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Locally Advanced Unresectable Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute 30
Large-scale testing (Phase 3)Looking for participantsNCT05954442
What this trial is testing

Everolimus With Investigator's Choice of Chemotherapy in Advanced Triple-Negative Breast Cancer (TNBC) With Luminal Androgen Receptor (LAR) Subtype

Who this might be right for
Triple Negative Breast CancerMetastatic Breast CancerMutation
Fudan University 203
Testing effectiveness (Phase 2)Study completedNCT00166543
What this trial is testing

Three Doses of TAS-108 to Treat Recurrent or Recurrent Inoperable Breast Cancer

Who this might be right for
Breast Cancer
SRI International 146
Large-scale testing (Phase 3)Active Not RecruitingNCT03997123
What this trial is testing

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Who this might be right for
Triple Negative Breast Neoplasms
AstraZeneca 923
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