Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies”

136 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 136 results

Testing effectiveness (Phase 2)Looking for participantsNCT05636215
What this trial is testing

A First-in-human Study of IBI354 in Subjects with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 368
Early research (Phase 1)Not Yet RecruitingNCT07797907
What this trial is testing

This Clinical Study is to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Antitumor Activity of BD200 in Participants With Advanced or Metastatic Cancer.

Who this might be right for
Solid Tumor (Phase I)
Biolojic Design Ltd. 110
Testing effectiveness (Phase 2)Ended earlyNCT03149549
What this trial is testing

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Who this might be right for
Solid Tumor, AdultBreast CancerNon Small Cell Lung Cancer+2 more
CytomX Therapeutics 99
Early research (Phase 1)Looking for participantsNCT06349408
What this trial is testing

IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Fortvita Biologics (USA)Inc. 250
Testing effectiveness (Phase 2)Ended earlyNCT00130936
What this trial is testing

Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates

Who this might be right for
Gastric CancerEsophageal CancerTumors
AHS Cancer Control Alberta 50
Early research (Phase 1)Looking for participantsNCT07612176
What this trial is testing

NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

Who this might be right for
Locally Advanced (Unresectable) or Metastatic Solid Tumors
NEOK Bio, Inc. 155
Testing effectiveness (Phase 2)Ended earlyNCT03138083
What this trial is testing

OMO-1 in Solid Malignancies

Who this might be right for
Neoplasms
Octimet Oncology N.V. 40
Large-scale testing (Phase 3)Study completedNCT04799249
What this trial is testing

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC)

Who this might be right for
TNBC - Triple-Negative Breast CancerBreast Cancer
G1 Therapeutics, Inc. 194
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07623707
What this trial is testing

FG-B901 Monotherapy or Combination With Chemotherapy in Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor
FutureGen Biopharmaceutical (Beijing) Co., Ltd 264
Early research (Phase 1)Looking for participantsNCT06963281
What this trial is testing

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

Who this might be right for
Solid Tumors
Fortvita Biologics (USA)Inc. 285
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03489369
What this trial is testing

Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Who this might be right for
Metastatic CancerSolid TumorLymphoma
Symphogen A/S 15
Testing effectiveness (Phase 2)UnknownNCT05842785
What this trial is testing

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

Who this might be right for
Has a Pathologically Documented Unresectable Locally Advanced or Metastatic Solid Tumor or Lymphoma
Tyligand Bioscience (Shanghai) Limited 162
Testing effectiveness (Phase 2)Study completedNCT06170190
What this trial is testing

A Multicentre,Study of IBI133 in Subjects WithUnresectable, Locally Advanced or Metastatic SolidTumours

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 19
Testing effectiveness (Phase 2)Study completedNCT02401815
What this trial is testing

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Who this might be right for
Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc. 51
Testing effectiveness (Phase 2)Study completedNCT04521179
What this trial is testing

Study of KN026 Combined With KN046 in Patients With Locally Advanced HER2-positive Solid Tumors

Who this might be right for
HER2-positive Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd 102
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)UnknownNCT05105464
What this trial is testing

Investigate the Safety of SYHA1815 in Subjects With Unresectable Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Unresectable Carcinoma
Shanghai Runshi Pharmaceutical Technology Co., Ltd 97
Testing effectiveness (Phase 2)Looking for participantsNCT06244771
What this trial is testing

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Who this might be right for
Advanced Solid Tumors With KRAS G12C MutationsSolid Tumor, AdultUnresectable Solid Tumor+5 more
Frontier Medicines Corporation 403
Early research (Phase 1)Study completedNCT04094506
What this trial is testing

Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Astellas Pharma Inc 9
Next Page
150