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Results for “Locally Advanced /Metastatic Solid Tumors”

756 trials

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Showing 20 of 756 results

Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Testing effectiveness (Phase 2)Study completedNCT02810418
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Who this might be right for
NeoplasmsPancreatic Neoplasms
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT01170897
What this trial is testing

Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Halozyme Therapeutics 27
Testing effectiveness (Phase 2)Looking for participantsNCT07296341
What this trial is testing

HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Pancreatic Cancer With
Shanghai Hengrui Pharmaceutical Co., Ltd. 60
Early research (Phase 1)Looking for participantsNCT06686745
What this trial is testing

Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd. 130
Testing effectiveness (Phase 2)Looking for participantsNCT06293651
What this trial is testing

Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DA-4505 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
Dong-A ST Co., Ltd. 125
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Testing effectiveness (Phase 2)Looking for participantsNCT07189871
What this trial is testing

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Who this might be right for
Castration-Resistant Prostate Cancer (CRPC)Colorectal CancerNSCLC (Non-small Cell Lung Cancer)+7 more
Radiopharm Theranostics, Ltd 61
Testing effectiveness (Phase 2)Active Not RecruitingNCT04396821
What this trial is testing

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced CancerGastric CancerGastroesophageal-junction Cancer+1 more
Transcenta Therapeutics (Hangzhou) Co., Ltd. 150
Early research (Phase 1)Ended earlyNCT02110563
What this trial is testing

Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma

Who this might be right for
Solid TumorsMultiple MyelomaNon-Hodgkins Lymphoma+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 50
Early research (Phase 1)Ended earlyNCT02122146
What this trial is testing

PF-06664178 In Patients With Advanced Solid Tumors

Who this might be right for
Neoplasms
Pfizer 31
Early research (Phase 1)WithdrawnNCT05010096
What this trial is testing

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center
Early research (Phase 1)Study completedNCT01075464
What this trial is testing

The Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Cancers
Genentech, Inc. 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
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