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Results for “Locally Advanced Bladder Urothelial Carcinoma”

107 trials

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Showing 20 of 107 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT03421652
What this trial is testing

Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo

Who this might be right for
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7Stage III Bladder Urothelial Carcinoma AJCC v6 and v7Stage IV Bladder Urothelial Carcinoma AJCC v7
Barbara Ann Karmanos Cancer Institute 20
Testing effectiveness (Phase 2)Study completedNCT01090466
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Cardiff University 15
Early research (Phase 1)Ended earlyNCT03915405
What this trial is testing

KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer

Who this might be right for
Urothelial Carcinoma
Kyowa Kirin, Inc. 16
Large-scale testing (Phase 3)Study completedNCT00033436
What this trial is testing

Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer

Who this might be right for
Bladder Cancer
Mount Vernon Cancer Centre at Mount Vernon Hospital 330
Testing effectiveness (Phase 2)Study completedNCT02236195
What this trial is testing

Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes

Who this might be right for
Urothelial Carcinoma
Mirati Therapeutics Inc. 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT05544552
What this trial is testing

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaSolid Tumor+11 more
Tyra Biosciences, Inc 310
Testing effectiveness (Phase 2)Study completedNCT00077688
What this trial is testing

TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitional Cell Carcinoma of the Urothelium

Who this might be right for
Bladder NeoplasmsUreteral NeoplasmsUrethral Neoplasms+1 more
Achieve Life Sciences 44
Testing effectiveness (Phase 2)Study completedNCT00526656
What this trial is testing

Sunitinib in Treating Patients With Locally Advanced Bladder Cancer

Who this might be right for
Bladder Cancer
Case Comprehensive Cancer Center 9
Testing effectiveness (Phase 2)Ended earlyNCT03324282
What this trial is testing

First-line Gemcitabine/Cisplatin +/- Avelumab in Locally Advanced or Metastatic Bladder Carcinoma

Who this might be right for
Bladder Carcinoma
University Hospital, Bordeaux 65
Early research (Phase 1)Active Not RecruitingNCT03170960
What this trial is testing

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Urothelial CarcinomaRenal Cell CarcinomaNon-Small Cell Lung Cancer+11 more
Exelixis 914
Testing effectiveness (Phase 2)Study completedNCT00055835
What this trial is testing

S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium

Who this might be right for
Bladder CancerUrethral Cancer
SWOG Cancer Research Network 7
Testing effectiveness (Phase 2)WithdrawnNCT03935347
What this trial is testing

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Who this might be right for
Metastatic Bladder Urothelial CarcinomaMetastatic Renal Pelvis Urothelial CarcinomaMetastatic Ureter Urothelial Carcinoma+3 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)UnknownNCT04047693
What this trial is testing

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Who this might be right for
Muscle Invasive Bladder CancerUrothelial CarcinomaNeoadjuvant Chemotherapy
Pusan National University Yangsan Hospital 32
Testing effectiveness (Phase 2)UnknownNCT00005958
What this trial is testing

Combination Chemotherapy Plus Filgrastim in Treating Patients With Locally Recurrent or Advanced Urothelium Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and Ureter
Amgen
Testing effectiveness (Phase 2)Study completedNCT01282463
What this trial is testing

Study of Ramucirumab or Icrucumab (IMC-18F1) With Docetaxel or Docetaxel Alone as Second-Line Therapy in Participants With Bladder,Urethra, Ureter, or Renal Pelvis Carcinoma

Who this might be right for
Carcinoma of Urinary TractUrethral CarcinomaCarcinoma of Ureter+1 more
Eli Lilly and Company 148
Large-scale testing (Phase 3)UnknownNCT00146276
What this trial is testing

Adjuvant Versus Progression-Triggered Gemcitabine Monotherapy for Locally Advanced Bladder Cancer

Who this might be right for
Bladder CancerCarcinoma, Transitional Cell
Association of Urologic Oncology (AUO) 178
Early research (Phase 1)Study completedNCT00623064
What this trial is testing

Lapatinib, Cisplatin, Gemcitabine as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and Ureter
European Organisation for Research and Treatment of Cancer - EORTC 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03601455
What this trial is testing

Radiation Therapy and Durvalumab With or Without Tremelimumab in Treating Participants With Unresectable, Locally Advanced, or Metastatic Bladder Cancer

Who this might be right for
Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Stage IVA Bladder Cancer AJCC v8+1 more
Jonsson Comprehensive Cancer Center 13
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