Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Colon Cancer”

292 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 292 results

Testing effectiveness (Phase 2)Ended earlyNCT05678257
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal NeoplasmsColorectal Adenocarcinoma+2 more
NuCana plc 180
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Testing effectiveness (Phase 2)UnknownNCT05732493
What this trial is testing

Short-course Radiotherapy Combined With Chemotherapy and Pd-1 Inhibitor for Locally Advanced Colon Cancer(TORCH-C)

Who this might be right for
Locally Advanced Colon Cancer
Fudan University 120
Testing effectiveness (Phase 2)Study completedNCT00022698
What this trial is testing

Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 67
Early research (Phase 1)Looking for participantsNCT07348211
What this trial is testing

First in Human Study of SIM0610 in Solid Tumors

Who this might be right for
Advanced Solid TumoursNon-Small Cell Lung CancerColorectal Cancer+2 more
Jiangsu Simcere Pharmaceutical Co., Ltd. 260
Testing effectiveness (Phase 2)Study completedNCT01227707
What this trial is testing

Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Ended earlyNCT01347645
What this trial is testing

Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer

Who this might be right for
Colon CancerRectal Cancer
Eisai Inc. 82
Early research (Phase 1)Active Not RecruitingNCT07457541
What this trial is testing

Molecular Imaging of Fibroblast Activation Protein Expression Using Labeled Technetium-99m HYNIC-FAPI

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Pancreas Cancer, MetastaticBreast Cancer (Locally Advanced or Metastatic)+1 more
Tomsk National Research Medical Center of the Russian Academy of Sciences 15
Early research (Phase 1)Looking for participantsNCT06440005
What this trial is testing

Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Who this might be right for
CancerAdvanced CancerLocally Advanced Carcinoma+8 more
Angiex, Inc. 80
Large-scale testing (Phase 3)Looking for participantsNCT06293625
What this trial is testing

Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More

Who this might be right for
Colon Cancer
Centre Hospitalier Universitaire Dijon 150
Testing effectiveness (Phase 2)UnknownNCT03280407
What this trial is testing

NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal NeoplasmColorectal CancerRectal Neoplasms+4 more
Zealand University Hospital 124
Testing effectiveness (Phase 2)WithdrawnNCT00070434
What this trial is testing

S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network
Testing effectiveness (Phase 2)Looking for participantsNCT07255664
What this trial is testing

A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC

Who this might be right for
Metastatic Colorectal CancerProstate Cancer MetastaticProstate Cancer Locally Advanced
Curacell Holding AB 12
Not applicableLooking for participantsNCT06613165
What this trial is testing

Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer

Who this might be right for
Immune-related Adverse EventNeoadjuvant TherapydMMR Colorectal Cancer
Xijing Hospital 100
Early research (Phase 1)Looking for participantsNCT07094204
What this trial is testing

Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Who this might be right for
Solid TumorNon-Small-Cell Lung CancerPancreatic Ductal Adenocarcinoma+1 more
Astellas Pharma Inc 364
Post-approval studies (Phase 4)Ended earlyNCT00216424
What this trial is testing

Capecitabine (Xeloda) and Radiation for Patients With Rectosigmoid Carcinoma

Who this might be right for
Colorectal Cancer
James A. Haley Veterans Administration Hospital 40
Load More Results