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Results for “Locally Advanced Colorectal Carcinoma”

323 trials

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Showing 20 of 323 results

Testing effectiveness (Phase 2)Ended earlyNCT05678257
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal NeoplasmsColorectal Adenocarcinoma+2 more
NuCana plc 180
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Testing effectiveness (Phase 2)Active Not RecruitingNCT04301557
What this trial is testing

PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
DMMR Colorectal CancerMSI-H Colorectal CancerLocally Advanced Colorectal Cancer
Sun Yat-sen University 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT04864067
What this trial is testing

No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Servicio de Salud Metropolitano Sur Oriente 73
Large-scale testing (Phase 3)Looking for participantsNCT06207981
What this trial is testing

Phase III Study Evaluating Induction Chemotherapy Followed by Chemoradiotherapy Compared to Standard Chemoradiotherapy for Locally Advanced SCCA

Who this might be right for
Anal Cancer
Federation Francophone de Cancerologie Digestive 310
Testing effectiveness (Phase 2)Study completedNCT00022698
What this trial is testing

Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 67
Early research (Phase 1)Looking for participantsNCT07348211
What this trial is testing

First in Human Study of SIM0610 in Solid Tumors

Who this might be right for
Advanced Solid TumoursNon-Small Cell Lung CancerColorectal Cancer+2 more
Jiangsu Simcere Pharmaceutical Co., Ltd. 260
Testing effectiveness (Phase 2)Study completedNCT01227707
What this trial is testing

Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Ended earlyNCT00671645
What this trial is testing

Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy

Who this might be right for
Rectal Cancer
Austrian Breast & Colorectal Cancer Study Group 8
Early research (Phase 1)Active Not RecruitingNCT07457541
What this trial is testing

Molecular Imaging of Fibroblast Activation Protein Expression Using Labeled Technetium-99m HYNIC-FAPI

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Pancreas Cancer, MetastaticBreast Cancer (Locally Advanced or Metastatic)+1 more
Tomsk National Research Medical Center of the Russian Academy of Sciences 15
Early research (Phase 1)Looking for participantsNCT06440005
What this trial is testing

Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Who this might be right for
CancerAdvanced CancerLocally Advanced Carcinoma+8 more
Angiex, Inc. 80
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
pMMRMSSMSI-L+1 more
Zhejiang University 50
Testing effectiveness (Phase 2)UnknownNCT03280407
What this trial is testing

NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal NeoplasmColorectal CancerRectal Neoplasms+4 more
Zealand University Hospital 124
Testing effectiveness (Phase 2)WithdrawnNCT00070434
What this trial is testing

S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network
Testing effectiveness (Phase 2)Looking for participantsNCT07255664
What this trial is testing

A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC

Who this might be right for
Metastatic Colorectal CancerProstate Cancer MetastaticProstate Cancer Locally Advanced
Curacell Holding AB 12
Not applicableLooking for participantsNCT06613165
What this trial is testing

Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer

Who this might be right for
Immune-related Adverse EventNeoadjuvant TherapydMMR Colorectal Cancer
Xijing Hospital 100
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