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Results for “Locally Advanced Cutaneous Squamous Cell Carcinoma”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Study completedNCT03284424
What this trial is testing

Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 159
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT04204837
What this trial is testing

Nivolumab for Treatment of Squamous Cell Carcinoma of the Skin

Who this might be right for
Squamous Cell Carcinoma of the Skin
Salzburger Landeskliniken 61
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06418724
What this trial is testing

Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Melanoma and Skin Cancer Trials Limited 27
Early research (Phase 1)Study completedNCT03590054
What this trial is testing

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Stage III Cutaneous MelanomaStage IV Cutaneous MelanomaLocally Advanced Melanoma+18 more
Rahul Aggarwal 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07228442
What this trial is testing

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Philogen S.p.A. 92
Testing effectiveness (Phase 2)Ended earlyNCT04812535
What this trial is testing

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Who this might be right for
SCC - Squamous Cell Carcinoma of Skin
InflaRx GmbH 30
Not applicableStudy completedNCT02324608
What this trial is testing

Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
Rutgers, The State University of New Jersey 15
Large-scale testing (Phase 3)Study completedNCT03833167
What this trial is testing

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Who this might be right for
Carcinoma, Squamous Cell
Merck Sharp & Dohme LLC 450
Testing effectiveness (Phase 2)Study completedNCT01979211
What this trial is testing

Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Cancer
University of Cincinnati 24
Testing effectiveness (Phase 2)Looking for participantsNCT04349436
What this trial is testing

Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies

Who this might be right for
Merkel Cell CarcinomaBasal Cell CarcinomaLocally Advanced Cutaneous Squamous Cell Carcinoma+1 more
Replimune, Inc. 90
Testing effectiveness (Phase 2)Ended earlyNCT04799054
What this trial is testing

TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+4 more
Ascendis Pharma Oncology Division A/S 188
Testing effectiveness (Phase 2)Active Not RecruitingNCT04315701
What this trial is testing

A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer

Who this might be right for
Recurrent Skin Squamous Cell CarcinomaResectable Skin Squamous Cell CarcinomaStage I Skin Cancer+2 more
University of Southern California 35
Not applicableNot Yet RecruitingNCT06971848
What this trial is testing

Evaluation of Skin Tests in Biotherapy Allergies

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckMelanoma NeoplasmsSmall Cell Bronchial Carcinomas+13 more
University Hospital, Angers 70
Testing effectiveness (Phase 2)Looking for participantsNCT07042295
What this trial is testing

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Who this might be right for
Locally Recurrent Skin Squamous Cell CarcinomaMetastatic Skin Squamous Cell Carcinoma
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Not applicableNo Longer AvailableNCT03492489
What this trial is testing

Expanded Access Protocol for Cemiplimab in Metastatic or Locally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)UnknownNCT02268747
What this trial is testing

Efficacy and Safety of Dacomitinib in the Treatment of Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 43
Testing effectiveness (Phase 2)Study completedNCT02760498
What this trial is testing

Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Advanced Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals 432
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