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Results for “Locally Advanced Cutaneous Squamous Cell Carcinoma”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Study completedNCT03108131
What this trial is testing

Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors

Who this might be right for
Skin Squamous Cell CarcinomaAppendix AdenocarcinomaRare Lesion+9 more
M.D. Anderson Cancer Center 49
Early research (Phase 1)Study completedNCT04870840
What this trial is testing

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

Who this might be right for
Locally Advanced Head and Neck Squamous Cell CarcinomaLocally Advanced Hypopharyngeal Squamous Cell CarcinomaLocally Advanced Laryngeal Squamous Cell Carcinoma+16 more
M.D. Anderson Cancer Center 3
Early research (Phase 1)Looking for participantsNCT05085496
What this trial is testing

Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC

Who this might be right for
Locally Advanced Skin Squamous Cell CarcinomaResectable Skin Squamous Cell CarcinomaUnresectable Skin Squamous Cell Carcinoma
City of Hope Medical Center 12
Not applicableStudy completedNCT03836105
What this trial is testing

CemiplimAb Survivorship Epidemiology

Who this might be right for
Cutaneous Squamous Cell CarcinomaBasal Cell Carcinoma
Regeneron Pharmaceuticals 287
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)Looking for participantsNCT07228442
What this trial is testing

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Philogen S.p.A. 92
Testing effectiveness (Phase 2)Temporarily pausedNCT07042295
What this trial is testing

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Who this might be right for
Locally Recurrent Skin Squamous Cell CarcinomaMetastatic Skin Squamous Cell Carcinoma
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Not applicableNo Longer AvailableNCT03492489
What this trial is testing

Expanded Access Protocol for Cemiplimab in Metastatic or Locally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals
Large-scale testing (Phase 3)Active Not RecruitingNCT05078047
What this trial is testing

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Who this might be right for
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck Cancer+12 more
UNICANCER 646
Not applicableLooking for participantsNCT07215988
What this trial is testing

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

Who this might be right for
Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
Ohio State University Comprehensive Cancer Center 70
Large-scale testing (Phase 3)Study completedNCT03833167
What this trial is testing

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Who this might be right for
Carcinoma, Squamous Cell
Merck Sharp & Dohme LLC 450
Testing effectiveness (Phase 2)Active Not RecruitingNCT05888844
What this trial is testing

Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Incyte Corporation 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT05620134
What this trial is testing

Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
CancerTumor, SolidAdvanced Solid Tumor+19 more
Salubris Biotherapeutics Inc 263
Large-scale testing (Phase 3)Ended earlyNCT06295809
What this trial is testing

(Neo)Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)

Who this might be right for
Carcinoma, Squamous CellSkin Neoplasms
Merck Sharp & Dohme LLC 46
Not applicableStudy completedNCT02324608
What this trial is testing

Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
Rutgers, The State University of New Jersey 15
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Study completedNCT02964559
What this trial is testing

Pembrolizumab in Patients With Locally Advanced or Metastatic Skin Cancer

Who this might be right for
Recurrent Skin CarcinomaSkin Squamous Cell Carcinoma
Emory University 11
Testing effectiveness (Phase 2)Ended earlyNCT04799054
What this trial is testing

TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+4 more
Ascendis Pharma Oncology Division A/S 188
Testing effectiveness (Phase 2)UnknownNCT02268747
What this trial is testing

Efficacy and Safety of Dacomitinib in the Treatment of Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 43
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