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Results for “Locally Advanced Esophageal Squamous Cell Carcinoma”

269 trials

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Showing 20 of 269 results

Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Testing effectiveness (Phase 2)Study completedNCT04732494
What this trial is testing

Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 125
Testing effectiveness (Phase 2)Looking for participantsNCT07435454
What this trial is testing

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Jiangsu Cancer Institute & Hospital 22
Testing effectiveness (Phase 2)WithdrawnNCT02041819
What this trial is testing

Neoadjuvant Chemotherapy of Nimotuzumab Plus Nab-Paclitaxel in Squamous Cell Carcinoma of Esophagus

Who this might be right for
Squamous Cell Carcinoma of Esophagus
Zhejiang University
Not applicableLooking for participantsNCT07549100
What this trial is testing

Efficacy and Safety of Tislelizumab Plus Chemotherapy as Conversion Therapy in Unresectable Locally Advanced ESCC

Who this might be right for
Locally Advanced Esophageal Squamous Cell Carcinoma
Shandong Provincial Hospital 30
Testing effectiveness (Phase 2)Study completedNCT00021047
What this trial is testing

Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor

Who this might be right for
Esophageal CancerExtrahepatic Bile Duct CancerGastric Cancer+3 more
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)Looking for participantsNCT06601309
What this trial is testing

Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Fujian Medical University Union Hospital 90
Large-scale testing (Phase 3)Study completedNCT01107639
What this trial is testing

Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Cancer
Swiss Cancer Institute 297
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06588335
What this trial is testing

BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Henan Provincial People's Hospital 20
Testing effectiveness (Phase 2)UnknownNCT05424432
What this trial is testing

Short Course Neoadjuvant Chemo-radiotherapy Plus Toripalimab for Locally Advanced Resectble Squamous Cell Carcinoma of Esophagus

Who this might be right for
Locally Advanced Esophageal Carcinoma
Jiangsu Cancer Institute & Hospital 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07584031
What this trial is testing

Adebrelimab Plus Full-course Neoadjuvant Therapy for Resectable Locally Advanced ESCC (Phase 2)

Who this might be right for
ESCC
Tianjin Medical University Cancer Institute and Hospital 200
Testing effectiveness (Phase 2)Ended earlyNCT04424641
What this trial is testing

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumor(s)Prostate CancerEsophageal Cancer+5 more
Genmab 48
Testing effectiveness (Phase 2)Looking for participantsNCT06339619
What this trial is testing

Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur, Gimeracil and Oteracil Potassium Capsules for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 32
Large-scale testing (Phase 3)Looking for participantsNCT06354530
What this trial is testing

Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Neoadjuvant TherapyEsophageal Squamous Cell Carcinoma
Army Medical Center of PLA 266
Large-scale testing (Phase 3)Looking for participantsNCT04807673
What this trial is testing

Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Tianjin Medical University Cancer Institute and Hospital 342
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Large-scale testing (Phase 3)Study completedNCT00655876
What this trial is testing

Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Cancer
Radiation Therapy Oncology Group 344
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Testing effectiveness (Phase 2)Active Not RecruitingNCT06888531
What this trial is testing

Prospective Phase II Clinical Study of Neoadjuvant Chemoradiotherapy Combined With PD-1/PD-L1 Inhibitors in the Treatment of Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Malignant Neoplasm Primary
Henan Cancer Hospital 30
Early research (Phase 1)Ended earlyNCT00368329
What this trial is testing

Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal NeoplasmsCarcinoma, Squamous CellAdenocarcinoma+1 more
Stanford University 4
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