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Results for “Locally Advanced Gastroesophageal Junction Adenocarcinoma”

241 trials

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Showing 20 of 241 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT06396585
What this trial is testing

The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric Junction

Who this might be right for
Immunotherapy Gastroesophageal Junction
Fujian Cancer Hospital 28
Testing effectiveness (Phase 2)UnknownNCT04367025
What this trial is testing

Efficacy and Safety of Perioperative Chemotherapy Plus PD-1 Antibody in Gastric Cancer

Who this might be right for
Gastric Cancer
Chinese PLA General Hospital 70
Testing effectiveness (Phase 2)UnknownNCT05019794
What this trial is testing

Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaSolid Tumor
LianBio LLC 80
Large-scale testing (Phase 3)Study completedNCT05008783
What this trial is testing

AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 610
Large-scale testing (Phase 3)Not Yet RecruitingNCT07068516
What this trial is testing

Perioperative Tislelizumab Plus Chemotherapy Versus Chemotherapy Alone in MHC-II-Positive Gastric/GEJ Cancer

Who this might be right for
Gastric Cancer Stage
Xiangdong Cheng 470
Large-scale testing (Phase 3)Study completedNCT01107639
What this trial is testing

Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Cancer
Swiss Cancer Institute 297
Large-scale testing (Phase 3)Active Not RecruitingNCT04208347
What this trial is testing

Perioperative Treatment of Combined SOX With Apatinib and Camrelizumab for Oesophagogastric Cancer

Who this might be right for
Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
Ruijin Hospital 580
Testing effectiveness (Phase 2)Looking for participantsNCT06415669
What this trial is testing

Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric/Gastroesophageal Junction Adenocarcinoma
The First Affiliated Hospital of Xiamen University 30
Testing effectiveness (Phase 2)Study completedNCT00938470
What this trial is testing

Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal CancerGastric Cancer
Alliance for Clinical Trials in Oncology 73
Large-scale testing (Phase 3)Active Not RecruitingNCT05568095
What this trial is testing

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Who this might be right for
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Arcus Biosciences, Inc. 1,040
Large-scale testing (Phase 3)Ended earlyNCT01641939
What this trial is testing

Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 415
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06586294
What this trial is testing

Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 294
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07464756
What this trial is testing

SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer

Who this might be right for
Gastric Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University 80
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Testing effectiveness (Phase 2)Looking for participantsNCT05702229
What this trial is testing

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer
AstraZeneca 163
Testing effectiveness (Phase 2)Ended earlyNCT04363801
What this trial is testing

DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Who this might be right for
Gastric CancerGastric AdenocarcinomaGastroEsophageal Cancer
Leap Therapeutics, Inc. 247
Large-scale testing (Phase 3)Looking for participantsNCT06925243
What this trial is testing

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])Neoadjuvant TherapyAdjuvant Chemotherapy+3 more
Zuoyi Jiao 682
Testing effectiveness (Phase 2)UnknownNCT03349866
What this trial is testing

A Prospective Study of Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy for Siewert II ，III of Locally Advanced HER-2 Negative Adenocarcinoma at Gastroesophageal Junction

Who this might be right for
Gastroesophageal Junction Adenocarcinoma
Hebei Medical University 48
Testing effectiveness (Phase 2)Looking for participantsNCT04656041
What this trial is testing

Folfox+Irinotecan+Chemort In Esophageal Cancer

Who this might be right for
Gastroesophageal Junction AdenocarcinomaEsophagogastric Cancer
Massachusetts General Hospital 40
Testing effectiveness (Phase 2)UnknownNCT05218148
What this trial is testing

SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma

Who this might be right for
HER2-positiveLocally Advanced Solid TumorImmunotherapy+4 more
Aiping Zhou 44
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