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Results for “Locally Advanced Gastroesophageal Junction Adenocarcinoma”

227 trials

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Showing 20 of 227 results

Testing effectiveness (Phase 2)UnknownNCT04367025
What this trial is testing

Efficacy and Safety of Perioperative Chemotherapy Plus PD-1 Antibody in Gastric Cancer

Who this might be right for
Gastric Cancer
Chinese PLA General Hospital 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06396585
What this trial is testing

The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric Junction

Who this might be right for
Immunotherapy Gastroesophageal Junction
Fujian Cancer Hospital 28
Large-scale testing (Phase 3)Not Yet RecruitingNCT07362186
What this trial is testing

LM-108 in Combination With Toripalimab Versus Paclitaxel Injection for the Treatment of Subjects With CCR8-Positive Gastric and Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Locally Advanced or Metastatic GC and GCJ Adenocarcinoma
LaNova Medicines Limited 400
Testing effectiveness (Phase 2)Study completedNCT01896531
What this trial is testing

Ipatasertib (GDC-0068) in Combination With Fluoropyrimidine Plus Oxaliplatin in Participants With Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Gastric Cancer
Genentech, Inc. 153
Testing effectiveness (Phase 2)Looking for participantsNCT06985602
What this trial is testing

Adebrelimab With Chemoradiotherapy and Surgery for G/GEJ

Who this might be right for
Gastroesophageal AdenocarcinomaGastric Adenocarcinoma
Jiangsu Cancer Institute & Hospital 30
Large-scale testing (Phase 3)Study completedNCT05008783
What this trial is testing

AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 610
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Large-scale testing (Phase 3)Study completedNCT01107639
What this trial is testing

Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Cancer
Swiss Cancer Institute 297
Early research (Phase 1)Study completedNCT03821233
What this trial is testing

A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers

Who this might be right for
HER2-expressing Cancers
Zymeworks BC Inc. 112
Not applicableUnknownNCT04915807
What this trial is testing

Real-world Data (RWD) of Ramucirumab Plus Paclitaxel

Who this might be right for
Gastric CancerGastroesophageal Junction Adenocarcinoma
Hallym University Medical Center 222
Testing effectiveness (Phase 2)Study completedNCT00938470
What this trial is testing

Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal CancerGastric Cancer
Alliance for Clinical Trials in Oncology 73
Not applicableStudy completedNCT04192734
What this trial is testing

Retrospective Study of Ramucirumab and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Hallym University Medical Center 1,063
Testing effectiveness (Phase 2)UnknownNCT04202484
What this trial is testing

Tripletrumab Combined With Oxaliplatin and Teggio (SOX) in First-line Treatment of Gastric and Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer
RenJi Hospital 20
Testing effectiveness (Phase 2)Study completedNCT01262482
What this trial is testing

Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based Treatment

Who this might be right for
Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment)
Grupo Espanol Multidisciplinario del Cancer Digestivo 41
Early research (Phase 1)Study completedNCT02572687
What this trial is testing

Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaNon-Small Cell Lung Cancer+1 more
Eli Lilly and Company 85
Testing effectiveness (Phase 2)UnknownNCT05466019
What this trial is testing

A Prospective, Single Center Clinical Study of Toripalimab Combined With FLOT Regimen for Perioperative Treatment of PD-L1 Positive Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GEJ)

Who this might be right for
PD-L1 Positive Locally Advanced Patients With Resectable Gastric Cancer
The First Hospital of Jilin University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06238167
What this trial is testing

Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC

Who this might be right for
Gastric Cancer
First Affiliated Hospital of Wenzhou Medical University 40
Early research (Phase 1)Ended earlyNCT01705340
What this trial is testing

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionHER2-positive Breast CancerMale Breast Cancer+9 more
National Cancer Institute (NCI) 60
Testing effectiveness (Phase 2)Looking for participantsNCT05651594
What this trial is testing

Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+8 more
Roswell Park Cancer Institute
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