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Results for “Locally Advanced HPV Positive Oropharynx Cancer”

18 trials

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Showing 18 of 18 results

Testing effectiveness (Phase 2)Study completedNCT02048020
What this trial is testing

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the HypopharynxStage III Squamous Cell Carcinoma of the Larynx+13 more
Jonsson Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Looking for participantsNCT07195734
What this trial is testing

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Recurrent Head and Neck Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT05172245
What this trial is testing

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown PrimaryLocally Advanced Head and Neck Squamous Cell Carcinoma+23 more
National Cancer Institute (NCI) 46
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Not applicableActive Not RecruitingNCT02945631
What this trial is testing

Quarterback 2b - Sequential Therapy With Reduced Dose Chemoradiotherapy for HPV Oropharynx Cancer

Who this might be right for
Locally Advanced HPV Positive Oropharynx Cancer
Icahn School of Medicine at Mount Sinai 43
Testing effectiveness (Phase 2)Ended earlyNCT01221753
What this trial is testing

Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckHuman Papilloma Virus
Dana-Farber Cancer Institute 7
Large-scale testing (Phase 3)Active Not RecruitingNCT01706939
What this trial is testing

The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer

Who this might be right for
Squamous Cell Carcinomas
Icahn School of Medicine at Mount Sinai 23
Early research (Phase 1)Study completedNCT02113878
What this trial is testing

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckHPV Positive Oropharyngeal Squamous Cell CarcinomaHypopharyngeal Cancer+3 more
Dana-Farber Cancer Institute 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT01898494
What this trial is testing

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the OropharynxStage IVA Squamous Cell Carcinoma of the Oropharynx+1 more
ECOG-ACRIN Cancer Research Group 519
Very early researchEnded earlyNCT04630353
What this trial is testing

A Study HB-201 in Patients With Newly Diagnosed HPV16+ Oropharynx or Locally Advanced Cervical Cancer

Who this might be right for
HPV 16+ Confirmed Oropharynx Cancer and Cervical Cancer
Hookipa Biotech GmbH 10
Not applicableWithdrawnNCT03611205
What this trial is testing

Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced Oropharyngeal Cancer Undergoing Chemoradiation Therapy

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT03342911
What this trial is testing

Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

Who this might be right for
Name Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaStage II Oropharyngeal Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma+19 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 34
Early research (Phase 1)Active Not RecruitingNCT05973487
What this trial is testing

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more
TScan Therapeutics, Inc. 840
Large-scale testing (Phase 3)Active Not RecruitingNCT03811015
What this trial is testing

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
National Cancer Institute (NCI) 636
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07172256
What this trial is testing

CUE-101with Pembrolizumab for LA-HPV+HNSCCs

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaNew Diagnosis Tumor+1 more
Yale University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Not applicableWithdrawnNCT04140513
What this trial is testing

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Oropharyngeal Squamous Cell Carcinoma+5 more
Ohio State University Comprehensive Cancer Center
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