Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Head and Neck Cancer”

1,027 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 1,027 results

Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Testing effectiveness (Phase 2)Looking for participantsNCT06959108
What this trial is testing

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Groupe Oncologie Radiotherapie Tete et Cou 106
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Testing effectiveness (Phase 2)UnknownNCT06235918
What this trial is testing

Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomasResectable Head and Neck Squamous-cell Carcinoma
Xiang Lu 30
Post-approval studies (Phase 4)UnknownNCT03691441
What this trial is testing

Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Cancer
Universitätsklinikum Hamburg-Eppendorf 280
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Study completedNCT00098345
What this trial is testing

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Who this might be right for
Thyroid Cancer
Genzyme, a Sanofi Company 40
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Testing effectiveness (Phase 2)Study completedNCT01592721
What this trial is testing

Radiation and Cetuximab Plus Intratumoral EGFR Antisense DNA in Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Squamous Cell CarcinomaHead and Neck Cancer
The University of Texas Health Science Center at San Antonio 6
Testing effectiveness (Phase 2)Looking for participantsNCT06752798
What this trial is testing

Bone Marrow Protective Effect of Trilaciclib in Postoperative CCRT for LA-HNSCC

Who this might be right for
Head and Neck Cancer Squamous Cell Carcinoma
Hunan Cancer Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07189871
What this trial is testing

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Who this might be right for
Castration-Resistant Prostate Cancer (CRPC)Colorectal CancerNSCLC (Non-small Cell Lung Cancer)+7 more
Radiopharm Theranostics, Ltd 61
Testing effectiveness (Phase 2)Study completedNCT04356170
What this trial is testing

Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma

Who this might be right for
Cancer of Head and Neck
Groupe Oncologie Radiotherapie Tete et Cou 105
Very early researchEnded earlyNCT01111942
What this trial is testing

A Pilot Study of Induction Chemotherapy Followed by Surgery for Locally Advanced Resectable Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
Southern Illinois University 4
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07677475
What this trial is testing

MRG003 Plus Toripalimab Versus Toripalimab as Neoadjuvant Therapy for PD-L1-Positive, Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Dongguan People's Hospital 65
Large-scale testing (Phase 3)Active Not RecruitingNCT02999087
What this trial is testing

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

Who this might be right for
HNSCC
Groupe Oncologie Radiotherapie Tete et Cou 707
Testing effectiveness (Phase 2)UnknownNCT01291095
What this trial is testing

Accelerated Fractionation Radiotherapy (AFRT) Versus Concurrent Chemoradiotherapy (Crt) In Locally Advanced Head And Neck Squamous Cell Carcinoma

Who this might be right for
HEAD AND NECK CANCER
All India Institute of Medical Sciences 80
Early research (Phase 1)Ended earlyNCT01057277
What this trial is testing

RAD001, Cisplatin and Concurrent Radiation for Locally Advanced, Inoperable Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
howard safran 3
Testing effectiveness (Phase 2)Looking for participantsNCT07381075
What this trial is testing

A Phase II Clinical Trial of Anti-EGFR Antibody-drug Conjugate (ADC) Combined With or Without Immune Checkpoint Inhibitors in the Neoadjuvant Treatment of Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
West China Hospital 90
Testing effectiveness (Phase 2)Looking for participantsNCT06056336
What this trial is testing

Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell CarcinomaNeoadjuvant ChemoimmunotherapyAdjuvant Therapy
Guo Xufeng 73
Early research (Phase 1)Study completedNCT01379339
What this trial is testing

Cabazitaxel - PF Induction Chemotherapy

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Krzysztof Misiukiewicz 40
Next Page