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Results for “Locally Advanced Head-and-Neck Cancer”

970 trials

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Showing 20 of 970 results

Very early researchActive Not RecruitingNCT05245682
What this trial is testing

Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer

Who this might be right for
Head and Neck Carcinoma of Unknown PrimaryLocally Advanced Head and Neck Squamous Cell CarcinomaLocally Advanced Hypopharyngeal Squamous Cell Carcinoma+3 more
Emory University 10
Early research (Phase 1)Study completedNCT03289962
What this trial is testing

Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
MelanomaNon-Small Cell Lung CancerBladder Cancer+5 more
Genentech, Inc. 272
Testing effectiveness (Phase 2)Study completedNCT03409848
What this trial is testing

Ipilimumab or FOLFOX in Combination With Nivolumab and Trastuzumab in HER2 Positive EsophagoGastric Adenocarcinoma

Who this might be right for
Gastric CancerEsophageal CancerAdenocarcinoma Gastric+3 more
AIO-Studien-gGmbH 97
Not applicableActive Not RecruitingNCT05459415
What this trial is testing

Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and NeckNeoadjuvant TherapyResection Margin
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 54
Testing effectiveness (Phase 2)Looking for participantsNCT07188103
What this trial is testing

Ivonescimab Plus Short-Course Hypofractionated Radiotherapy as Second-Line Therapy for Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Anhui Provincial Hospital 37
Testing effectiveness (Phase 2)Looking for participantsNCT06475300
What this trial is testing

BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

Who this might be right for
Non-small Cell Lung CancerNasopharyngeal CarcinomaSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 570
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07172256
What this trial is testing

CUE-101with Pembrolizumab for LA-HPV+HNSCCs

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaNew Diagnosis Tumor+1 more
Yale University 30
Testing effectiveness (Phase 2)Looking for participantsNCT06970353
What this trial is testing

Phase II Trial of Tunlametinib in NRAS-Mutant Advanced Thyroid Cancer

Who this might be right for
Radioactive Iodine-refractory, Differentiated Thyroid Cancer With NRAS MutationAdvanced PDTC or ATC With NRAS Mutation
Fudan University 40
Testing effectiveness (Phase 2)Study completedNCT00611754
What this trial is testing

Phase II Study of Oxaliplatin in Combination With 5-Fu in 1st Line Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Cancer
Sanofi 15
Testing effectiveness (Phase 2)Study completedNCT00022139
What this trial is testing

Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Who this might be right for
Esophageal CancerGastric Cancer
Alliance for Clinical Trials in Oncology 56
Testing effectiveness (Phase 2)Study completedNCT00851877
What this trial is testing

Nab-Paclitaxel, Cisplatin, and Cetuximab With Concurrent Radiation Therapy for Locally Advanced Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
University of Texas Southwestern Medical Center 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Study completedNCT00899054
What this trial is testing

Safety and Efficacy Study of P276-00 in Combination With Radiation in Subjects With Advanced Head and Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Piramal Enterprises Limited 23
Large-scale testing (Phase 3)Looking for participantsNCT05674305
What this trial is testing

Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy

Who this might be right for
Nasopharyngeal Carcinoma
Fudan University 366
Early research (Phase 1)Looking for participantsNCT05172245
What this trial is testing

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown PrimaryLocally Advanced Head and Neck Squamous Cell Carcinoma+23 more
National Cancer Institute (NCI) 46
Testing effectiveness (Phase 2)Study completedNCT01613768
What this trial is testing

Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer

Who this might be right for
Recurrent Salivary Gland CancerStage IVA Salivary Gland CancerStage IVB Salivary Gland Cancer+1 more
University of Washington 29
Testing effectiveness (Phase 2)Looking for participantsNCT06709417
What this trial is testing

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Shanghai Chest Hospital 52
Testing effectiveness (Phase 2)UnknownNCT04602013
What this trial is testing

Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Esophageal Squamous Cell Carcinoma
Sichuan Cancer Hospital and Research Institute 53
Testing effectiveness (Phase 2)UnknownNCT04514835
What this trial is testing

A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 44
Testing effectiveness (Phase 2)Study completedNCT00006081
What this trial is testing

Combination Chemotherapy in Treating Patients With Unresectable Locally Advanced or Metastatic Stomach Cancer

Who this might be right for
Esophageal CancerGastric Cancer
M.D. Anderson Cancer Center 37
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