Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Hepatocellular Carcinoma”

117 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 117 results

Testing effectiveness (Phase 2)Looking for participantsNCT07227012
What this trial is testing

Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Who this might be right for
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4 more
Pfizer 138
Early research (Phase 1)Study completedNCT02572687
What this trial is testing

Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaNon-Small Cell Lung Cancer+1 more
Eli Lilly and Company 85
Testing effectiveness (Phase 2)Looking for participantsNCT05733598
What this trial is testing

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Who this might be right for
Hepatocellular CarcinomaBiliary Tract Cancer
Replimune Inc. 60
Early research (Phase 1)Looking for participantsNCT07376707
What this trial is testing

TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors

Who this might be right for
CRC (Colorectal Cancer)Melanoma (Skin Cancer)HCC - Hepatocellular Carcinoma+1 more
Hefei TG ImmunoPharma Co., Ltd. 194
Testing effectiveness (Phase 2)Looking for participantsNCT05440708
What this trial is testing

TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tvardi Therapeutics, Incorporated 178
Testing effectiveness (Phase 2)Ended earlyNCT03422679
What this trial is testing

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Who this might be right for
Breast CancerColorectal CancerAdenoid Cystic Carcinoma+5 more
Cellestia Biotech AG 79
Early research (Phase 1)Active Not RecruitingNCT03170960
What this trial is testing

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Urothelial CarcinomaRenal Cell CarcinomaNon-Small Cell Lung Cancer+11 more
Exelixis 914
Not applicableLooking for participantsNCT06028724
What this trial is testing

A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)

Who this might be right for
Solid TumorAdvanced Solid TumorLocally Advanced Solid Tumor+11 more
Centro di Riferimento Oncologico - Aviano 782
Not applicableLooking for participantsNCT06873269
What this trial is testing

Holmium-166 Transarterial Radioembolization for the Treatment of Hepatocellular Carcinoma

Who this might be right for
Locally Advanced Hepatocellular CarcinomaLiver CirrhosisNon-metastatic Hepatocellular Carcinoma
Universitair Ziekenhuis Brussel 100
Large-scale testing (Phase 3)UnknownNCT01135056
What this trial is testing

Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Singapore General Hospital 360
Testing effectiveness (Phase 2)Study completedNCT00238394
What this trial is testing

Cediranib Maleate in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer
National Cancer Institute (NCI) 44
Early research (Phase 1)UnknownNCT04417764
What this trial is testing

TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.

Who this might be right for
Advanced Hepatocellular Carcinoma
Central South University 10
Early research (Phase 1)UnknownNCT02403544
What this trial is testing

Phase I Study of Image-Guided Radiation Concurrent With Double-Agent Chemotherapy for Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Chinese Academy of Medical Sciences 30
Testing effectiveness (Phase 2)Study completedNCT04401800
What this trial is testing

Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaUnresectable Hepatocellular CarcinomaMetastatic Hepatocellular Carcinoma
BeiGene 64
Large-scale testing (Phase 3)Not Yet RecruitingNCT07356037
What this trial is testing

Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma

Who this might be right for
CachexiaHepatocellular Carcinoma
Changchun GeneScience Pharmaceutical Co., Ltd. 68
Not applicableUnknownNCT03881501
What this trial is testing

Evaluate the Treatment With Sintilimab Injection Plus Endostar in Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectable
Huazhong University of Science and Technology 2
Not applicableNot Yet RecruitingNCT06971848
What this trial is testing

Evaluation of Skin Tests in Biotherapy Allergies

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckMelanoma NeoplasmsSmall Cell Bronchial Carcinomas+13 more
University Hospital, Angers 70
Testing effectiveness (Phase 2)Ended earlyNCT00427973
What this trial is testing

AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer+1 more
National Cancer Institute (NCI) 17
Large-scale testing (Phase 3)Looking for participantsNCT05078047
What this trial is testing

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Who this might be right for
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck Cancer+12 more
UNICANCER 646
Testing effectiveness (Phase 2)Study completedNCT00867321
What this trial is testing

Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Liver Cancer
Alliance for Clinical Trials in Oncology 24
Load More Results