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Results for “Locally Advanced Intrahepatic Cholangiocarcinoma”

22 trials

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Showing 20 of 22 results

Not applicableNot Yet RecruitingNCT07208526
What this trial is testing

Trial of Surgical Decision-Making Guided by TDTP-RECIST

Who this might be right for
Intrahepatic Cholangiocarcinoma (Icc)Conversion TherapyTDTP-RECIST+1 more
Shanghai Zhongshan Hospital 270
Testing effectiveness (Phase 2)Looking for participantsNCT05422690
What this trial is testing

The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer

Who this might be right for
Intrahepatic Cholangiocarcinoma
Inova Health Care Services 16
Testing effectiveness (Phase 2)Looking for participantsNCT06859684
What this trial is testing

Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)

Who this might be right for
Intrahepatic Cholangiocarcinoma (Icc)HAICDurvalumab
West China Hospital 25
Not applicableNot Yet RecruitingNCT06910722
What this trial is testing

Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and Chemotherapy

Who this might be right for
Liver Transplantation in Locally Advanced Intrahepatic Cholangiocarcinoma
Assistance Publique - Hôpitaux de Paris 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06946849
What this trial is testing

Second-line Regimen Combined With Radiotherapy Versus Without Radiotherapy in Patients With Locally Advanced/Oligometastatic ICC After Failure of First-line Treatment：an Open-label, Randomized, Controlled Phase II Clinical Study

Who this might be right for
Intrahepatic Cholangiocarcinoma (Icc)
Shanghai Zhongshan Hospital 76
Early research (Phase 1)Looking for participantsNCT06160752
What this trial is testing

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

Who this might be right for
Locally Advanced CholangiocarcinomaIntrahepatic CholangiocarcinomaSolid Tumor+1 more
Tyra Biosciences, Inc 40
Large-scale testing (Phase 3)Ended earlyNCT04163900
What this trial is testing

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
NuCana plc 773
Not applicableLooking for participantsNCT06140134
What this trial is testing

Liver Transplantation in Intrahepatic Cholangiocarcinoma

Who this might be right for
Intrahepatic CholangiocarcinomaCholangiocarcinoma, Intrahepatic
Rutgers, The State University of New Jersey 30
Not applicableNo Longer AvailableNCT04087876
What this trial is testing

Expanded Access Use of Derazantinib for Advanced Intrahepatic Cholangiocarcinoma (iCCA) With FGFR Genomic Alterations

Who this might be right for
Intrahepatic Cholangiocarcinoma
Basilea Pharmaceutica
Testing effectiveness (Phase 2)Ended earlyNCT02254681
What this trial is testing

Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Allina Health System 6
Testing effectiveness (Phase 2)Ended earlyNCT05565794
What this trial is testing

Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

Who this might be right for
Intrahepatic CholangiocarcinomaFGFR2 Gene MutationFGFR2 Gene Rearrangement+1 more
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 2
Large-scale testing (Phase 3)Ended earlyNCT00658593
What this trial is testing

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
NCIC Clinical Trials Group 19
Testing effectiveness (Phase 2)Ended earlyNCT06370663
What this trial is testing

First-line Treatment for Unresectable Locally Advanced Distal Cholangiocarcinoma Combining Radiotherapy and HAIC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shandong Cancer Hospital and Institute 1
Testing effectiveness (Phase 2)Study completedNCT03044587
What this trial is testing

Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer

Who this might be right for
Adenocarcinoma MetastaticBiliary Tract CancerAdenocarcinoma of the Biliary Tract+4 more
AIO-Studien-gGmbH 93
Early research (Phase 1)Looking for participantsNCT06058663
What this trial is testing

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaOligometastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Mayo Clinic 16
Early research (Phase 1)Active Not RecruitingNCT04708067
What this trial is testing

Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaMetastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+3 more
M.D. Anderson Cancer Center 2
Early research (Phase 1)Ended earlyNCT03267940
What this trial is testing

Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma

Who this might be right for
Cholangiocarcinoma Non-resectableCholangiocarcinoma, IntrahepaticCholangiocarcinoma, Extrahepatic+1 more
Halozyme Therapeutics 85
Testing effectiveness (Phase 2)UnknownNCT05620498
What this trial is testing

Tislelizumab Combined With Lenvatinib and GEMOX Versus Tislelizumab Combined With GEMOX in Conversion Therapy of ICC and GBC.

Who this might be right for
Potentially Resectable Locally Advanced Intrahepatic Cholangiocarcinoma and Gallbladder Cancer
Tianjin Medical University Cancer Institute and Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT05655949
What this trial is testing

Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio

Who this might be right for
Bile Duct CancerCholangiocarcinomaCholangiocarcinoma Non-resectable+2 more
Beth Israel Deaconess Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06178588
What this trial is testing

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

Who this might be right for
Locally Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRecurrent Cholangiocarcinoma+4 more
University of Kansas Medical Center 22
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