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Results for “Locally Advanced Low Rectal Adenocarcinoma”

13 trials

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Showing 13 of 13 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07277842
What this trial is testing

PD-1 + FOLFOXIRI vs CAPOX as Total Neoadjuvant Therapy for pMMR Low Rectal Cancer

Who this might be right for
Locally Advanced Low Rectal AdenocarcinomapMMR (Microsatellite Stable Rectal Cancer)
Sun Yat-sen University 382
Post-approval studies (Phase 4)Enrolling By InvitationNCT06931808
What this trial is testing

Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer

Who this might be right for
Localized Advanced Rectal Adenocarcinoma
First Affiliated Hospital of Ningbo University 20
Testing effectiveness (Phase 2)Looking for participantsNCT07458529
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant TherapyImmunotherapy+3 more
Seventh Medical Center of PLA General Hospital 50
Testing effectiveness (Phase 2)Study completedNCT06108596
What this trial is testing

Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Mid-low Locally Advanced Rectal Cancer - a Single-center, Single-arm, Open-label Clinical Trail

Who this might be right for
Locally Advanced Rectal Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University 33
Not applicableUnknownNCT03042000
What this trial is testing

Multicenter, Prospective, RCT：Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant Chemoradiation
Peking Union Medical College Hospital 1,200
Testing effectiveness (Phase 2)Ended earlyNCT04066894
What this trial is testing

Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study

Who this might be right for
Low Anterior Resection SyndromeMalignant Anal NeoplasmMalignant Bladder Neoplasm+8 more
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06872606
What this trial is testing

Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 33
Early research (Phase 1)Looking for participantsNCT07104604
What this trial is testing

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Toripalimab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

Who this might be right for
Rectal Cancer
Affiliated Cancer Hospital of Shantou University Medical College 59
Testing effectiveness (Phase 2)Looking for participantsNCT07292298
What this trial is testing

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Who this might be right for
Rectal AdenocarcinomaRectal Cancer
University of Colorado, Denver 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07397442
What this trial is testing

Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaRectal Cancer Stage IIRectal Cancer Stage III
Beijing Friendship Hospital 19
Testing effectiveness (Phase 2)UnknownNCT01227239
What this trial is testing

Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting

Who this might be right for
Rectal Carcinoma
Japan Clinical Cancer Research Organization 45
Testing effectiveness (Phase 2)UnknownNCT05858567
What this trial is testing

Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50