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Results for “Locally Advanced Malignant Skin Neoplasm”

61 trials

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Showing 20 of 61 results

Not applicableUnknownNCT00264056
What this trial is testing

Efficacy of Chemotherapy Combined With Regional Hypothermia in Advanced Malignant Melanoma Patients With Progressive Soft Tissue Metastases

Who this might be right for
Advanced Metastastic Malignant MelanomaRefractory to First-Line Chemotherapy Irresectable Progressive Soft Tissue Metastases
Fachklinik Hornheide an der Universität Münster 26
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Not applicableLooking for participantsNCT06971848
What this trial is testing

Evaluation of Skin Tests in Biotherapy Allergies

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckMelanoma NeoplasmsSmall Cell Bronchial Carcinomas+13 more
University Hospital, Angers 70
Not applicableLooking for participantsNCT06075524
What this trial is testing

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Lung Carcinoma+7 more
Mayo Clinic 500
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Ended earlyNCT05714553
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Who this might be right for
Advanced CancerAdvanced Solid TumorNeoplasm Malignant+14 more
NuCana plc 19
Testing effectiveness (Phase 2)Ended earlyNCT04260802
What this trial is testing

Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Who this might be right for
CancerNeoplasmsMetastatic Cancer+16 more
Ocellaris Pharma, Inc. 73
Testing effectiveness (Phase 2)Active Not RecruitingNCT04550494
What this trial is testing

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more
National Cancer Institute (NCI) 29
Early research (Phase 1)Looking for participantsNCT07137416
What this trial is testing

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast Carcinoma+13 more
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT03428802
What this trial is testing

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationLocally Advanced Solid Neoplasm+17 more
Rutgers, The State University of New Jersey 21
Early research (Phase 1)WithdrawnNCT04498520
What this trial is testing

Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+32 more
Pamela Munster
Testing effectiveness (Phase 2)Study completedNCT00421811
What this trial is testing

ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan

Who this might be right for
Neoplasms
Adherex Technologies, Inc. 56
Testing effectiveness (Phase 2)Study completedNCT01693068
What this trial is testing

Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma

Who this might be right for
N-Ras Mutated Locally Advanced or Metastasis Malignant Cutaneous Melanoma
EMD Serono 194
Testing effectiveness (Phase 2)Looking for participantsNCT07280832
What this trial is testing

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma and Urinary Tract Tumors

Who this might be right for
Unresectable Locally Advanced or Metastatic MelanomaUnresectable Locally Advanced or Metastatic Urinary Tract Tumors
Shanghai JMT-Bio Inc. 500
Testing effectiveness (Phase 2)Study completedNCT01654692
What this trial is testing

A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma

Who this might be right for
Metastatic Malignant Melanoma
Italian Network for Tumor Biotherapy 86
Testing effectiveness (Phase 2)UnknownNCT03666325
What this trial is testing

Immunotherapy +/- EGFR Inhibitor In Advanced/Metastatic cSCC: Tackling Primary And Secondary Resistance

Who this might be right for
Skin Neoplasm
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 43
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