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Results for “Locally Advanced Malignant Solid Neoplasm”

183 trials

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Showing 20 of 183 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04632108
What this trial is testing

A 1/2 Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ASKB589 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Malignant Solid Tumor
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 199
Early research (Phase 1)Study completedNCT02227940
What this trial is testing

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmALK PositiveMetastatic Pancreatic Adenocarcinoma+2 more
Roswell Park Cancer Institute 38
Testing effectiveness (Phase 2)Looking for participantsNCT06172478
What this trial is testing

HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaHead and Neck Cancer+11 more
Daiichi Sankyo 740
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Study completedNCT01325558
What this trial is testing

ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Malignant NeoplasmMalignant Solid Tumour
Altor BioScience 30
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Early research (Phase 1)UnknownNCT05276609
What this trial is testing

ARTEMIS-001: Phase 1 Study of the HS-20093 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Hansoh Biomedical Co., Ltd 177
Early research (Phase 1)Active Not RecruitingNCT04050709
What this trial is testing

QUILT-3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers

Who this might be right for
Locally Advanced Solid TumorMetastatic CancerSolid Tumor
ImmunityBio, Inc. 16
Early research (Phase 1)Study completedNCT03489343
What this trial is testing

Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Who this might be right for
Metastatic CancerSolid TumorLymphoma
Symphogen A/S 24
Testing effectiveness (Phase 2)Looking for participantsNCT06416007
What this trial is testing

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

Who this might be right for
CancerMetastatic CancerLocally Advanced+2 more
University of Cincinnati 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT05544552
What this trial is testing

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaSolid Tumor+11 more
Tyra Biosciences, Inc 310
Early research (Phase 1)Study completedNCT04672434
What this trial is testing

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 48
Early research (Phase 1)WithdrawnNCT05010096
What this trial is testing

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center
Early research (Phase 1)Ended earlyNCT03295942
What this trial is testing

OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors

Who this might be right for
Locally Advanced Malignant NeoplasmMetastatic Cancer
OncoMed Pharmaceuticals, Inc. 24
Early research (Phase 1)Study completedNCT01482377
What this trial is testing

RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin

Who this might be right for
Neoplasms
Hoffmann-La Roche 145
Testing effectiveness (Phase 2)Ended earlyNCT05357898
What this trial is testing

Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Adult Solid Tumor
SQZ Biotechnologies 20
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Testing effectiveness (Phase 2)Ended earlyNCT03422679
What this trial is testing

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Who this might be right for
Breast CancerColorectal CancerAdenoid Cystic Carcinoma+5 more
Cellestia Biotech AG 79
Not applicableLooking for participantsNCT06028724
What this trial is testing

A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)

Who this might be right for
Solid TumorAdvanced Solid TumorLocally Advanced Solid Tumor+11 more
Centro di Riferimento Oncologico - Aviano 782
Testing effectiveness (Phase 2)Looking for participantsNCT05991583
What this trial is testing

A Clinical Trial to Evaluate Effect of IBB0979 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
SUNHO（China）BioPharmaceutical CO., Ltd. 25
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