Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Melanoma”

153 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 153 results

Early research (Phase 1)Ended earlyNCT00492440
What this trial is testing

Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer

Who this might be right for
Kidney CancerMelanoma (Skin)
Cytheris SA 9
Early research (Phase 1)Study completedNCT02457793
What this trial is testing

The Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Genentech, Inc. 24
Testing effectiveness (Phase 2)Looking for participantsNCT06172478
What this trial is testing

HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaHead and Neck Cancer+11 more
Daiichi Sankyo 740
Early research (Phase 1)Active Not RecruitingNCT05653882
What this trial is testing

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Who this might be right for
Solid TumorNon Small Cell Lung CancerMelanoma+2 more
Asher Biotherapeutics, Inc. 552
Early research (Phase 1)Study completedNCT02821000
What this trial is testing

Safety and Efficacy Study of Pembrolizumab (MK-3475) in Chinese Participants With Locally Advanced or Metastatic Melanoma (MK-3475-151/KEYNOTE-151)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 103
Testing effectiveness (Phase 2)UnknownNCT03013101
What this trial is testing

Safety and Efficacy of Recombinant Humanized Anti-PD-1 mAb for Patients With Locally Advanced or Metastatic Melanoma

Who this might be right for
Advanced MelanomaMetastatic Melanoma
Shanghai Junshi Bioscience Co., Ltd. 128
Large-scale testing (Phase 3)Study completedNCT02908672
What this trial is testing

Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma

Who this might be right for
Melanoma
Hoffmann-La Roche 514
Testing effectiveness (Phase 2)Looking for participantsNCT07280832
What this trial is testing

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma

Who this might be right for
Unresectable Locally Advanced or Metastatic Melanoma
Shanghai JMT-Bio Inc. 188
Testing effectiveness (Phase 2)Ended earlyNCT00707161
What this trial is testing

Radiation Therapy and Concurrent Cisplatin Chemotherapy for Locally Advanced or Metastatic Malignant Melanoma

Who this might be right for
CancerMelanoma
University of Utah 6
Early research (Phase 1)Study completedNCT01436656
What this trial is testing

A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant Melanoma

Who this might be right for
Melanoma and Metastatic Colorectal Cancer
Pfizer 107
Early research (Phase 1)Ended earlyNCT02387125
What this trial is testing

Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

Who this might be right for
SarcomaMelanomaNon-small Cell Lung Cancer+1 more
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 79
Early research (Phase 1)Looking for participantsNCT07376707
What this trial is testing

TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors

Who this might be right for
CRC (Colorectal Cancer)Melanoma (Skin Cancer)HCC - Hepatocellular Carcinoma+1 more
Hefei TG ImmunoPharma Co., Ltd. 194
Testing effectiveness (Phase 2)Ended earlyNCT03224208
What this trial is testing

Vemurafenib Plus Cobimetinib in Advanced or Metastatic Melanoma Patients

Who this might be right for
MelanomaMelanoma (Skin)Melanoma Stage
Fondazione Melanoma Onlus 9
Early research (Phase 1)Study completedNCT02573259
What this trial is testing

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

Who this might be right for
Part 1MELANOMASCCHN+6 more
Pfizer 147
Testing effectiveness (Phase 2)Ended earlyNCT01777776
What this trial is testing

Safety and Efficacy of LEE011 and LGX818 in Patients With BRAF Mutant Melanoma.

Who this might be right for
Locally Advanced Metastatic BRAF Mutant Melanoma
Array BioPharma 28
Not applicableLooking for participantsNCT06028724
What this trial is testing

A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)

Who this might be right for
Solid TumorAdvanced Solid TumorLocally Advanced Solid Tumor+11 more
Centro di Riferimento Oncologico - Aviano 782
Early research (Phase 1)Ended earlyNCT02313012
What this trial is testing

Safety and PK Study of CC-90003 in Relapsed/Refractory Solid Tumors

Who this might be right for
Neoplasm Metastasis
Celgene 19
Testing effectiveness (Phase 2)Study completedNCT00116597
What this trial is testing

Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma

Who this might be right for
Melanoma
University Hospital, Basel, Switzerland 15
Testing effectiveness (Phase 2)Looking for participantsNCT05081609
What this trial is testing

Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+10 more
Ascendis Pharma Oncology Division A/S 345
Not applicableLooking for participantsNCT04045691
What this trial is testing

Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment

Who this might be right for
Melanoma Stage IVMelanoma Stage III
Pierre Fabre Pharma GmbH 750
Load More Results