Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Rectal Adenocarcinoma”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07596290
What this trial is testing

Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC

Who this might be right for
Locally Advanced Rectal AdenocarcinomaNeoadjuvant ChemoradiationNeoadjuvant Immunotherapy
Beijing Friendship Hospital 342
Early research (Phase 1)Study completedNCT04672434
What this trial is testing

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 48
Testing effectiveness (Phase 2)Study completedNCT00307736
What this trial is testing

Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer

Who this might be right for
Rectal CancerAdenocarcinoma of the Rectum
Massachusetts General Hospital 32
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Ended earlyNCT00004193
What this trial is testing

ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Alabama at Birmingham 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07543848
What this trial is testing

A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer

Who this might be right for
Rectal NeoplasmsRectal Adenocarcinoma
Chongqing University Cancer Hospital 20
Early research (Phase 1)Ended earlyNCT04406857
What this trial is testing

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

Who this might be right for
Locally Advanced Rectal CarcinomaRectal AdenocarcinomaStage II Rectal Cancer AJCC v8+1 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Study completedNCT05622357
What this trial is testing

Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Carcinoma
National Cancer Institute, Egypt 51
Early research (Phase 1)WithdrawnNCT04632199
What this trial is testing

Study to Assess the Safety and Efficacy of Intravenous Injection of the Imaging Agent 111In-IPN01087 in Patients With Locally Advanced or Metastatic Pancreatic or Colorectal Cancer.

Who this might be right for
Pancreatic Ductal AdenocarcinomaColorectal Cancer
Ipsen
Testing effectiveness (Phase 2)UnknownNCT01227239
What this trial is testing

Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting

Who this might be right for
Rectal Carcinoma
Japan Clinical Cancer Research Organization 45
Testing effectiveness (Phase 2)Looking for participantsNCT07292298
What this trial is testing

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Who this might be right for
Rectal AdenocarcinomaRectal Cancer
University of Colorado, Denver 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07161115
What this trial is testing

Involve-site Radiotherapy Combined With Chemotherapy and Immunotherapy as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Longhao Li 60
Testing effectiveness (Phase 2)Study completedNCT00080834
What this trial is testing

DJ-927 as Second-Line Therapy in Treating Patients With Progressive Locally Advanced or Metastatic Colorectal Adenocarcinoma

Who this might be right for
Colorectal Cancer
Daiichi Sankyo
Large-scale testing (Phase 3)Looking for participantsNCT04749108
What this trial is testing

Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma

Who this might be right for
Locally Advanced Malignant NeoplasmRectal Carcinoma
Institut du Cancer de Montpellier - Val d'Aurelle 1,075
Early research (Phase 1)Active Not RecruitingNCT03821935
What this trial is testing

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 364
Not applicableLooking for participantsNCT05772481
What this trial is testing

Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma

Who this might be right for
Rectal Cancer
Centre Paul Strauss 50
Testing effectiveness (Phase 2)Study completedNCT00003950
What this trial is testing

Irinotecan and Cyclosporine in Treating Patients With Metastatic, Advanced or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Chicago 16
Testing effectiveness (Phase 2)Ended earlyNCT04066894
What this trial is testing

Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study

Who this might be right for
Low Anterior Resection SyndromeMalignant Anal NeoplasmMalignant Bladder Neoplasm+8 more
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Ended earlyNCT05678257
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal NeoplasmsColorectal Adenocarcinoma+2 more
NuCana plc 180
Next Page