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Results for “Locally Advanced Rectal Cancer (LARC)”

45 trials

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Showing 20 of 45 results

Testing effectiveness (Phase 2)UnknownNCT05575635
What this trial is testing

Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC

Who this might be right for
Rectal Cancer
Henan Provincial People's Hospital 40
Testing effectiveness (Phase 2)Study completedNCT04009876
What this trial is testing

Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Fundación de investigación HM 30
Testing effectiveness (Phase 2)UnknownNCT01952951
What this trial is testing

Preoperative Chemoradiation Followed by Chemotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Rectal NeoplasmsAdenocarcinoma
National Cancer Center, Korea 110
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Not applicableLooking for participantsNCT07393048
What this trial is testing

Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant Therapy for Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Beijing Friendship Hospital 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07314528
What this trial is testing

Evaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal Cancer

Who this might be right for
Rectal Cancer PatientsObesity &Amp; OverweightLocally Advanced Rectal Cancer (LARC)+2 more
St. James's Hospital, Ireland 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381777
What this trial is testing

XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS or MSI-Low Locally Advanced Rectal Cancer (LARC) Patients

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Gruppo Oncologico Italiano di Ricerca Clinica 270
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07176182
What this trial is testing

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

Who this might be right for
Rectal Cancer PatientsRectal Cancer Stage IIRectal Cancer Stage III
Sixth Affiliated Hospital, Sun Yat-sen University 236
Early research (Phase 1)Looking for participantsNCT06459869
What this trial is testing

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Akamis Bio 30
Not applicableStudy completedNCT07351708
What this trial is testing

Development and Validation of a Post-operative Risk Of Local Recurrence Model Integrating Serology and Evalution (PROMISE) in Local Advanced Rectal Cancer Receiving Neoadjuvant Therapy: a Multicenter Study

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Cai Zerong 2,315
Not applicableLooking for participantsNCT06761287
What this trial is testing

Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Centre Hospitalier Universitaire Saint Pierre 20
Testing effectiveness (Phase 2)Looking for participantsNCT06940388
What this trial is testing

Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
brenner baruch 134
Not applicableStudy completedNCT07049627
What this trial is testing

AI-Based Prediction of Pathological Response in Rectal Cancer Patients Receiving Total Neoadjuvant Therapy

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Ankara Etlik City Hospital 93
Testing effectiveness (Phase 2)Looking for participantsNCT06864013
What this trial is testing

SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University 116
Not applicableLooking for participantsNCT07269249
What this trial is testing

Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
National Cancer Institute, Naples 50
Not applicableStudy completedNCT05893667
What this trial is testing

Evaluation of Inflammatory Markers in LARC Patients

Who this might be right for
Locally Advanced Rectal Cancer
Hospital Pedro Hispano 245
Testing effectiveness (Phase 2)Looking for participantsNCT06911684
What this trial is testing

Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.

Who this might be right for
Rectal Cancer Patients
Sun Yat-sen University 88
Testing effectiveness (Phase 2)UnknownNCT05307198
What this trial is testing

Rectal Artery Infusion Chemotherapy Combined With Anti-PD1 Antibody for MSS LARC

Who this might be right for
Rectal Neoplasms
Second Affiliated Hospital, School of Medicine, Zhejiang University 38
Testing effectiveness (Phase 2)Looking for participantsNCT06516445
What this trial is testing

SCRT Followed by Camrelizumab Combined With Fluzoparib and Chemotherapy as Neoadjuvant Therapy for LARC

Who this might be right for
Colorectal Cancer
Huazhong University of Science and Technology 33
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