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Results for “Locally Advanced Rectal Cancer (LARC)”

57 trials

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Showing 20 of 57 results

Testing effectiveness (Phase 2)Looking for participantsNCT07646639
What this trial is testing

Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC

Who this might be right for
Rectal CancerRadiotherapy
The First Affiliated Hospital with Nanjing Medical University 122
Testing effectiveness (Phase 2)Looking for participantsNCT07198165
What this trial is testing

SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC

Who this might be right for
Rectal CancerRectal AdenocarcinomaRectal Cancer, Radiotherapy+6 more
Ruijin Hospital 104
Testing effectiveness (Phase 2)UnknownNCT05575635
What this trial is testing

Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC

Who this might be right for
Rectal Cancer
Henan Provincial People's Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06864013
What this trial is testing

SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University 116
Not applicableLooking for participantsNCT06761287
What this trial is testing

Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Centre Hospitalier Universitaire Saint Pierre 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT07596290
What this trial is testing

Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC

Who this might be right for
Locally Advanced Rectal AdenocarcinomaNeoadjuvant ChemoradiationNeoadjuvant Immunotherapy
Beijing Friendship Hospital 342
Testing effectiveness (Phase 2)Looking for participantsNCT06802666
What this trial is testing

Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal CancerNeoadjuvant Therapy
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 45
Testing effectiveness (Phase 2)Study completedNCT04009876
What this trial is testing

Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Fundación de investigación HM 30
Not applicableUnknownNCT05070832
What this trial is testing

Hyperthermia Combined With Neoadjuvant Radiochemotherapy for LARC

Who this might be right for
HyperthermiaRadiotherapy
Peking University Third Hospital 142
Testing effectiveness (Phase 2)Looking for participantsNCT07347951
What this trial is testing

A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Wenzhou Medical University 30
Not applicableLooking for participantsNCT07393048
What this trial is testing

Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant Therapy for Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Beijing Friendship Hospital 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)Looking for participantsNCT07176182
What this trial is testing

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

Who this might be right for
Rectal Cancer PatientsRectal Cancer Stage IIRectal Cancer Stage III
Sixth Affiliated Hospital, Sun Yat-sen University 236
Not applicableLooking for participantsNCT06653452
What this trial is testing

Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Peking Union Medical College Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07040098
What this trial is testing

Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 228
Testing effectiveness (Phase 2)Active Not RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
Testing effectiveness (Phase 2)Study completedNCT03156036
What this trial is testing

Preoperative CRT With Capecitabine ± Temozolomide in Patients With LARC

Who this might be right for
Advanced Rectal Cancer
Asan Medical Center 64
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Not applicableLooking for participantsNCT07269249
What this trial is testing

Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
National Cancer Institute, Naples 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175636
What this trial is testing

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Mismatch Repair-Proficient (pMMR) Rectal CancerNon-metastatic Rectal Cancer
Sun Yat-sen University 66
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