Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Skin Squamous Cell Carcinoma”

97 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 97 results

Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Testing effectiveness (Phase 2)Study completedNCT03284424
What this trial is testing

Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 159
Testing effectiveness (Phase 2)Ended earlyNCT04260802
What this trial is testing

Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Who this might be right for
CancerNeoplasmsMetastatic Cancer+16 more
Ocellaris Pharma, Inc. 73
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Very early researchStudy completedNCT04177498
What this trial is testing

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Thomas Jefferson University 3
Testing effectiveness (Phase 2)Ended earlyNCT05070247
What this trial is testing

TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Pancreatic CancerHepatocellular CancerMesothelioma+7 more
Takeda 61
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Early research (Phase 1)Temporarily pausedNCT03970382
What this trial is testing

Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors

Who this might be right for
Solid Tumor
PACT Pharma, Inc. 21
Testing effectiveness (Phase 2)Looking for participantsNCT04204837
What this trial is testing

Nivolumab for Treatment of Squamous Cell Carcinoma of the Skin

Who this might be right for
Squamous Cell Carcinoma of the Skin
Salzburger Landeskliniken 61
Early research (Phase 1)Study completedNCT01772004
What this trial is testing

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

Who this might be right for
Solid Tumors
EMD Serono Research & Development Institute, Inc. 1,756
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06418724
What this trial is testing

Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Melanoma and Skin Cancer Trials Limited 27
Early research (Phase 1)Looking for participantsNCT07229313
What this trial is testing

KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advance Solid Tumors
Kivu Bioscience Inc. 76
Early research (Phase 1)Study completedNCT03590054
What this trial is testing

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Stage III Cutaneous MelanomaStage IV Cutaneous MelanomaLocally Advanced Melanoma+18 more
Rahul Aggarwal 35
Early research (Phase 1)Looking for participantsNCT06545331
What this trial is testing

Study of XB010 in Subjects With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsEsophageal Squamous Cell CancerHead and Neck Squamous Cell Cancer+3 more
Exelixis 396
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07228442
What this trial is testing

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Philogen S.p.A. 92
Early research (Phase 1)Looking for participantsNCT07503808
What this trial is testing

IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

Who this might be right for
Esophageal Squamous Cell CarcinomaHigh Grade Serous Ovarian CancerHead and Neck Squamous Cell Carcinoma+5 more
IDEAYA Biosciences 150
Testing effectiveness (Phase 2)Ended earlyNCT04812535
What this trial is testing

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Who this might be right for
SCC - Squamous Cell Carcinoma of Skin
InflaRx GmbH 30
Not applicableStudy completedNCT02324608
What this trial is testing

Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
Rutgers, The State University of New Jersey 15
Load More Results