Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Skin Squamous Cell Carcinoma”

98 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 98 results

Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI) 150
Very early researchStudy completedNCT04177498
What this trial is testing

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Thomas Jefferson University 3
Testing effectiveness (Phase 2)UnknownNCT02268747
What this trial is testing

Efficacy and Safety of Dacomitinib in the Treatment of Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 43
Testing effectiveness (Phase 2)Ended earlyNCT04424641
What this trial is testing

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumor(s)Prostate CancerEsophageal Cancer+5 more
Genmab 48
Testing effectiveness (Phase 2)Looking for participantsNCT06580054
What this trial is testing

Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckRecurrent Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
University of Michigan Rogel Cancer Center 22
Large-scale testing (Phase 3)Study completedNCT03833167
What this trial is testing

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Who this might be right for
Carcinoma, Squamous Cell
Merck Sharp & Dohme LLC 450
Testing effectiveness (Phase 2)Study completedNCT03786237
What this trial is testing

Rigosertib for RDEB-SCC

Who this might be right for
Epidermolysis Bullosa DystrophicaSquamous Cell Carcinoma
Prof. Johann Bauer 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Not applicableUnknownNCT01586767
What this trial is testing

Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy

Who this might be right for
Adenoid Cystic CarcinomaSquamous Cell CarcinomaSinonasal Carcinoma+6 more
Massachusetts General Hospital 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Early research (Phase 1)Study completedNCT00010023
What this trial is testing

Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Cancer
NYU Langone Health
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT04305795
What this trial is testing

An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors

Who this might be right for
Recurrent Head and Neck Squamous Cell CarcinomaMetastatic Head-and-neck Squamous-cell CarcinomaLocally Advanced Cutaneous Squamous Cell Carcinoma+1 more
Rakuten Medical, Inc. 23
Early research (Phase 1)Study completedNCT03458117
What this trial is testing

T-VEC in Non-melanoma Skin Cancer

Who this might be right for
Non-melanoma Skin CancerBasal Cell CarcinomaSquamous Cell Carcinoma+2 more
University of Zurich 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT05888844
What this trial is testing

Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Incyte Corporation 63
Testing effectiveness (Phase 2)Looking for participantsNCT04204837
What this trial is testing

Nivolumab for Treatment of Squamous Cell Carcinoma of the Skin

Who this might be right for
Squamous Cell Carcinoma of the Skin
Salzburger Landeskliniken 61
Testing effectiveness (Phase 2)Ended earlyNCT04799054
What this trial is testing

TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+4 more
Ascendis Pharma Oncology Division A/S 188
Testing effectiveness (Phase 2)Study completedNCT00126555
What this trial is testing

Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced or Recurrent Squamous Cell Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
National Cancer Institute (NCI) 23
Early research (Phase 1)Study completedNCT02051751
What this trial is testing

Evaluate the Potential Benefit of the Addition of BYL719 to Paclitaxel in the Treatment of Breast Cancer and Head-and-neck Cancer

Who this might be right for
Neoplasms, Breast Neoplasms, Head and Neck Neoplasms
Novartis Pharmaceuticals 19
Load More Results