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Results for “Locally Advanced Solid Neoplasm”

721 trials

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Showing 20 of 721 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04632108
What this trial is testing

A 1/2 Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ASKB589 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Malignant Solid Tumor
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 199
Early research (Phase 1)Study completedNCT02827968
What this trial is testing

Phase 1 Study of Anti-PD-L1 Monoclonal Antibody KN035 to Treat Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
3D Medicines (Sichuan) Co., Ltd. 28
Early research (Phase 1)Study completedNCT03509012
What this trial is testing

Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckCarcinoma, Non-Small-Cell LungSmall Cell Lung Carcinoma
AstraZeneca 105
Early research (Phase 1)Study completedNCT02457793
What this trial is testing

The Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Genentech, Inc. 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Early research (Phase 1)Study completedNCT02227940
What this trial is testing

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmALK PositiveMetastatic Pancreatic Adenocarcinoma+2 more
Roswell Park Cancer Institute 38
Early research (Phase 1)Study completedNCT01071018
What this trial is testing

MK2206 in Locally Advanced or Metastatic Solid Tumors (2206-007)

Who this might be right for
Solid Tumors
Merck Sharp & Dohme LLC 24
Early research (Phase 1)Study completedNCT00004049
What this trial is testing

SR-45023A in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Genzyme, a Sanofi Company 36
Early research (Phase 1)Looking for participantsNCT07232524
What this trial is testing

BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 16
Testing effectiveness (Phase 2)Looking for participantsNCT06172478
What this trial is testing

HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaHead and Neck Cancer+11 more
Daiichi Sankyo 740
Early research (Phase 1)Active Not RecruitingNCT05653882
What this trial is testing

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Who this might be right for
Solid TumorNon Small Cell Lung CancerMelanoma+2 more
Asher Biotherapeutics, Inc. 552
Early research (Phase 1)Active Not RecruitingNCT04511845
What this trial is testing

A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
Chugai Pharmaceutical 113
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Study completedNCT02410512
What this trial is testing

Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Neoplasms
Genentech, Inc. 610
Early research (Phase 1)Study completedNCT01325558
What this trial is testing

ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Malignant NeoplasmMalignant Solid Tumour
Altor BioScience 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Early research (Phase 1)Looking for participantsNCT06246071
What this trial is testing

TYK-00540 in Adult Patients With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
TYK Medicines, Inc 156
Early research (Phase 1)Study completedNCT02304393
What this trial is testing

Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 140
Testing effectiveness (Phase 2)Study completedNCT01327612
What this trial is testing

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Who this might be right for
Advanced Solid TumorsCarcinoidColorectal Cancer+6 more
Amgen 12
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
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