Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Solid Tumor”

785 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 785 results

Early research (Phase 1)Study completedNCT00003742
What this trial is testing

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT01988896
What this trial is testing

Study of Atezolizumab in Combination With Cobimetinib in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 153
Early research (Phase 1)Study completedNCT00033241
What this trial is testing

Erlotinib Combined With Gemcitabine in Treating Patients With Newly Diagnosed Locally Advanced or Metastatic Pancreatic Cancer or Other Solid Tumors

Who this might be right for
Pancreatic CancerUnspecified Adult Solid Tumor, Protocol Specific
OSI Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07022002
What this trial is testing

SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors

Who this might be right for
Locally Advanced, Recurrent or Metastatic Malignancies
Shenyang Sunshine Pharmaceutical Co., LTD. 340
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Early research (Phase 1)Study completedNCT05323045
What this trial is testing

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

Who this might be right for
Solid Tumor
Byondis B.V. 31
Early research (Phase 1)Study completedNCT02650713
What this trial is testing

The Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 228
Early research (Phase 1)Looking for participantsNCT05458219
What this trial is testing

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 470
Early research (Phase 1)Looking for participantsNCT06493864
What this trial is testing

BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

Who this might be right for
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 21
Testing effectiveness (Phase 2)Looking for participantsNCT03556228
What this trial is testing

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Who this might be right for
Head and Neck CarcinomaAdenoid Cystic CarcinomaLung Cancer+22 more
VM Oncology, LLC 242
Testing effectiveness (Phase 2)UnknownNCT05268666
What this trial is testing

Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced Solid TumorMetastatic Solid Tumor
Jubilant Therapeutics Inc. 126
Early research (Phase 1)Active Not RecruitingNCT06328439
What this trial is testing

Evaluate ANS014004 in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
Avistone Biotechnology Co., Ltd. 40
Early research (Phase 1)Study completedNCT01032681
What this trial is testing

EMD 521873 in Advanced Solid Tumors, MTD Finding

Who this might be right for
Non-Hodgkin Lymphoma
Merck KGaA, Darmstadt, Germany 66
Early research (Phase 1)Looking for participantsNCT06536400
What this trial is testing

Phase I Study of HSK42360 in Solid Tumors With BRAF V600 Mutation

Who this might be right for
Solid Tumors
Haisco Pharmaceutical Group Co., Ltd. 316
Early research (Phase 1)Study completedNCT01068977
What this trial is testing

The Safety and Pharmacology of MetMAb (PRO143966), a Monovalent Antagonist Antibody to the Receptor C-Met, Administered Intravenously in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Cancers
Genentech, Inc. 44
Testing effectiveness (Phase 2)Ended earlyNCT00923247
What this trial is testing

A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC)

Who this might be right for
Medullary Thyroid Carcinoma
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Looking for participantsNCT07488676
What this trial is testing

ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

Who this might be right for
Gastric or Gastro-esophageal Junction (GEJ) AdenocarcinomaPancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 150
Early research (Phase 1)Study completedNCT01106508
What this trial is testing

A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsRecurrent or Refractory MedulloblastomaLocally Advanced or Metastatic Basal Cell Carcinoma
Novartis Pharmaceuticals 57
Early research (Phase 1)Study completedNCT02827968
What this trial is testing

Phase 1 Study of Anti-PD-L1 Monoclonal Antibody KN035 to Treat Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
3D Medicines (Sichuan) Co., Ltd. 28
Early research (Phase 1)Looking for participantsNCT06418061
What this trial is testing

Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
UnresectableLocally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 198
Next Page