Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Stage”

4,727 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 4,727 results

Testing effectiveness (Phase 2)UnknownNCT05133349
What this trial is testing

A Prospective Phase II Efficacy and Safety Study of Anlotinib in Metastatic or Locally Advanced Pheochromocytoma/ Paraganglioma : Open-label Single-arm, Exploratory Trial

Who this might be right for
Advanced or Metastatic Paraganglioma/ Pheochromocytoma
Nanjing First Hospital, Nanjing Medical University 20
Testing effectiveness (Phase 2)WithdrawnNCT02033538
What this trial is testing

Neoadjuvant Chemotherapy of Nanoparticle Albumin-bound Paclitaxel in Squamous Cell Carcinoma of Esophagus

Who this might be right for
Squamous Cell Carcinoma of Esophagus
Zhejiang University
Testing effectiveness (Phase 2)Study completedNCT03267121
What this trial is testing

Apatinib and Tegafur Gimeracil Oteracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 38
Testing effectiveness (Phase 2)UnknownNCT00178763
What this trial is testing

Hyperthermia With Chemotherapy for Locally Advanced or Metastatic Pancreas Cancer

Who this might be right for
Pancreatic Neoplasms
The University of Texas Health Science Center, Houston 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT06124378
What this trial is testing

Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer

Who this might be right for
Colonic NeoplasmsNeoadjuvant TherapyImmune Checkpoint Inhibitors
First Affiliated Hospital of Guangxi Medical University 60
Not applicableLooking for participantsNCT07096258
What this trial is testing

EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)
Hedera Dx SA 1,000
Testing effectiveness (Phase 2)UnknownNCT05241899
What this trial is testing

A Phase II Clinical Study of Fruquintinib Combined With RC48 in the Treatment of Previously Treated HER2-positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (G/GEJ) Cancer

Who this might be right for
Gastric Cancer
The First Affiliated Hospital of Zhengzhou University 56
Testing effectiveness (Phase 2)WithdrawnNCT03991104
What this trial is testing

SOX-based CRT for Esophageal Cancer.

Who this might be right for
Esophageal Cancer
Zhejiang Provincial People's Hospital
Early research (Phase 1)Study completedNCT00335998
What this trial is testing

Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic Malignancies

Who this might be right for
Recurrent Cervical CancerRecurrent Ovarian Epithelial CancerRecurrent Vaginal Cancer+15 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Looking for participantsNCT07182149
What this trial is testing

NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Who this might be right for
HNSCCESCCEsophageal Adenocarcinoma+7 more
Normunity AccelCo, Inc. 150
Testing effectiveness (Phase 2)Looking for participantsNCT06567015
What this trial is testing

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Pierre Fabre Medicament 171
Testing effectiveness (Phase 2)Study completedNCT00714025
What this trial is testing

A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of Chemotherapy

Who this might be right for
Transitional Cell Carcinoma
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 40
Testing effectiveness (Phase 2)Study completedNCT00890825
What this trial is testing

AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
AstraZeneca 88
Large-scale testing (Phase 3)Not Yet RecruitingNCT05610332
What this trial is testing

Clinical Efficacy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer With Different Immunotypes

Who this might be right for
Locally Advanced Gastric Cancer
Fujian Medical University 216
Testing effectiveness (Phase 2)Looking for participantsNCT07214987
What this trial is testing

PDT For Induction Therapy For Head And Neck Cancer

Who this might be right for
Squamous Cell CarcinomaHead and Neck Cancer Squamous Cell CarcinomaHead and Neck Cancer
Massachusetts General Hospital 26
Large-scale testing (Phase 3)Looking for participantsNCT06881784
What this trial is testing

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)Non-Small Cell Lung CancerNSCLC+2 more
Revolution Medicines, Inc. 590
Testing effectiveness (Phase 2)Looking for participantsNCT07423078
What this trial is testing

Window of Opportunity in Preserving Laryngeal Function Trial

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)Locally Advanced Laryngeal Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma
Matthew Spector 87
Not applicableEnded earlyNCT00727532
What this trial is testing

Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

Who this might be right for
Hereditary Clear Cell Renal Cell CarcinomaKidney Cancer
Northwestern University 9
Early research (Phase 1)Study completedNCT04975958
What this trial is testing

Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Adlai Nortye Biopharma Co., Ltd. 47
Early research (Phase 1)Study completedNCT01933568
What this trial is testing

Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm.

Who this might be right for
Inoperable Locally Advanced Non Small Cell Lung Cancer
The Netherlands Cancer Institute 15
Next Page