Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Stage”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT04577638
What this trial is testing

Accelerated Radio-Immunotherapy for Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer Stage III
Center Eugene Marquis 8
Early research (Phase 1)Study completedNCT01487785
What this trial is testing

Dose-escalation, and Safety Study of LDE225 and Gemcitabine in Locally Advanced or Metastatic Pancreatic Cancer Patients

Who this might be right for
Pancreatic Cancer
Novartis Pharmaceuticals 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT05445843
What this trial is testing

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Who this might be right for
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT05481476
What this trial is testing

Surufatinib Combined With Sintilimab and AG in First-line Therapy of Patients With Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Neoplasms
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Study completedNCT01596868
What this trial is testing

GP VS TP in the Treatment of Advanced Nasopharyngeal Carcinoma in Northwest China

Who this might be right for
Nasopharyngeal Squamous Cell CarcinomaToxicity Due to Radiotherapy
Air Force Military Medical University, China 60
Large-scale testing (Phase 3)UnknownNCT04780750
What this trial is testing

Concurent Chemoradiotherapy in Head and Neck Cancers

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Assiut University 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Testing effectiveness (Phase 2)Study completedNCT02990468
What this trial is testing

A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
BioMimetix JV, LLC 29
Testing effectiveness (Phase 2)Study completedNCT03370718
What this trial is testing

Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma

Who this might be right for
Metastatic Carcinoma in the Adrenal CortexStage III Adrenal Cortex Carcinoma AJCC v8Stage IV Adrenal Cortex Carcinoma AJCC v8+1 more
M.D. Anderson Cancer Center 18
Testing effectiveness (Phase 2)Study completedNCT00802945
What this trial is testing

Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Breast Cancer

Who this might be right for
TumorBreast Cancer
Nektar Therapeutics 70
Testing effectiveness (Phase 2)Study completedNCT00118157
What this trial is testing

Lapatinib and Tamoxifen in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Tamoxifen

Who this might be right for
Estrogen Receptor PositiveMale Breast CarcinomaProgesterone Receptor Positive+4 more
National Cancer Institute (NCI) 19
Early research (Phase 1)Looking for participantsNCT05989828
What this trial is testing

A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast Cancer
University of Southern California 20
Not applicableLooking for participantsNCT07795619
What this trial is testing

HCCANANO-HOPE1: IRE After Chemotherapy for Locally Advanced Unresectable Perihilar Cholangiocarcinoma

Who this might be right for
IRE
Tianjin Medical University Cancer Institute and Hospital 60
Testing effectiveness (Phase 2)Study completedNCT00025168
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Unresectable Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Wake Forest University Health Sciences 20
Testing effectiveness (Phase 2)UnknownNCT04571489
What this trial is testing

A Phase II Study of Gimatecan (ST1481) in Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Lee's Pharmaceutical Limited 60
Testing effectiveness (Phase 2)Ended earlyNCT05176925
What this trial is testing

Tislelizumab Combined With Sitravatinib as Consolidation Treatment Following Concurrent Chemoradiation in Patients With Locally Advanced, Unresectable NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Fudan University 5
Not applicableTemporarily pausedNCT05547347
What this trial is testing

Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Locally Advanced Breast CarcinomaResectable Breast Carcinoma
Mayo Clinic 15
Testing effectiveness (Phase 2)Ended earlyNCT03952325
What this trial is testing

Tesetaxel Plus 3 Different PD-(L)1 Inhibitors in Patients With Triple-Negative MBC and Tesetaxel Monotherapy in Patients With HER2-Negative MBC

Who this might be right for
Breast Cancer
Odonate Therapeutics, Inc. 294
Testing effectiveness (Phase 2)Study completedNCT02730546
What this trial is testing

Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery

Who this might be right for
Gastric Cardia AdenocarcinomaGastroesophageal Junction AdenocarcinomaStage IB Gastric Cancer AJCC v7+5 more
Mayo Clinic 31
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06599827
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC

Who this might be right for
Rectal Cancer
Shanghai Zhongshan Hospital 54
Next Page