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Results for “Locally Advanced Tumor”

6,259 trials

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Showing 20 of 6,259 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04603807
What this trial is testing

Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 217
Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Testing effectiveness (Phase 2)Looking for participantsNCT03624244
What this trial is testing

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)

Who this might be right for
Low Grade Endometrial Stromal Sarcoma
Centre Leon Berard 40
Not applicableWithdrawnNCT03942900
What this trial is testing

Immunomonitoring and Biomarker Research in Patients With Squamous Cell Anal Carcinoma

Who this might be right for
Anal Canal Cancer
Centre Hospitalier Universitaire de Besancon
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Testing effectiveness (Phase 2)Study completedNCT00807911
What this trial is testing

Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer

Who this might be right for
Rectal Cancer
Asan Medical Center 322
Testing effectiveness (Phase 2)UnknownNCT05267392
What this trial is testing

Neoadjuvant Immunotherapy With Durvalumab (MEDI4736) in Non-Surgical Early Stage or Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Followed by Radical Radiotherapy or Chemoradiotherapy

Who this might be right for
Non-small Cell Lung Cancer
Instituto Portugues de Oncologia, Francisco Gentil, Porto 30
Testing effectiveness (Phase 2)Ended earlyNCT00321308
What this trial is testing

Trial of Pemetrexed With or Without PF-3512676 in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small Cell Lung
Pfizer 36
Early research (Phase 1)Looking for participantsNCT06673017
What this trial is testing

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Pancreatic Ductal AdenocarcinomaBorderline Resectable Pancreatic AdenocarcinomaLocally Advanced Pancreatic Adenocarcinoma+1 more
PanTher Therapeutics 26
Not applicableStudy completedNCT00788489
What this trial is testing

A Prospective Study to Evaluate FDG-PET, Breast MRI, and Breast Ultrasonography in Monitoring Tumour Responses in Patients With Locally Advanced Breast Cancer (LABC) Undergoing Neoadjuvant Chemotherapy

Who this might be right for
Locally Advanced Breast Cancer
Ontario Clinical Oncology Group (OCOG) 49
Testing effectiveness (Phase 2)UnknownNCT03985891
What this trial is testing

The Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer

Who this might be right for
Colonic NeoplasmsChemotherapy Effect
Xiangya Hospital of Central South University 40
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Testing effectiveness (Phase 2)Looking for participantsNCT06959108
What this trial is testing

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Groupe Oncologie Radiotherapie Tete et Cou 106
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07107217
What this trial is testing

Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
Blokhin's Russian Cancer Research Center 40
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Not applicableStudy completedNCT06412874
What this trial is testing

Assessment of Supportive Care and Educational Needs to Guide Quality Care Improvements for Patients With Locally Advanced and Metastatic Bladder Cancer

Who this might be right for
Screening ToolFocus Group
Icahn School of Medicine at Mount Sinai 93
Testing effectiveness (Phase 2)Study completedNCT00669591
What this trial is testing

A Safety and Efficacy Study of Bavituximab Plus Docetaxel in Patients With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Peregrine Pharmaceuticals 46
Testing effectiveness (Phase 2)UnknownNCT05775874
What this trial is testing

Evaluate the Safety and Efficacy of AZD4547 Combination With Tislelizumab in Patients With mUC

Who this might be right for
Urothelial Carcinoma
Abbisko Therapeutics Co, Ltd 80
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