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Results for “Locally Advanced Unresectable Cholangiocarcinoma”

42 trials

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Showing 20 of 42 results

Early research (Phase 1)Ended earlyNCT01525069
What this trial is testing

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Who this might be right for
CholangiocarcinomaLiver Neoplasms
Washington University School of Medicine 27
Testing effectiveness (Phase 2)Ended earlyNCT00085410
What this trial is testing

Bortezomib in Treating Patients With Unresectable Locally Advanced or Metastatic Adenocarcinoma of the Bile Duct or Gallbladder

Who this might be right for
Adenocarcinoma of the Extrahepatic Bile DuctAdenocarcinoma of the GallbladderAdvanced Adult Primary Liver Cancer+7 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Looking for participantsNCT07359820
What this trial is testing

Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

Who this might be right for
FGFR2 Gene Fusion/RearrangementOther Solid Tumors, Adult
Elevar Therapeutics 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06855225
What this trial is testing

A Phase II Study of Single Tremelimumab With Regular Interval Durvalumab Plus Gemcitabine and Cisplatin in Locally Advanced Unresectable/Metastatic Combined Hepatocellular-cholangiocarcinoma

Who this might be right for
Combined Hepatocellular and Cholangiocarcinoma
Mehmet Akce 29
Testing effectiveness (Phase 2)Ended earlyNCT06370663
What this trial is testing

First-line Treatment for Unresectable Locally Advanced Distal Cholangiocarcinoma Combining Radiotherapy and HAIC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shandong Cancer Hospital and Institute 1
Testing effectiveness (Phase 2)Study completedNCT01093222
What this trial is testing

Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or Cholangiocarcinoma

Who this might be right for
Extrahepatic Bile Duct AdenocarcinomaGallbladder AdenocarcinomaGallbladder Adenocarcinoma With Squamous Metaplasia+6 more
National Cancer Institute (NCI) 40
Large-scale testing (Phase 3)Study completedNCT00513539
What this trial is testing

Biliary Stenting With or Without Photodynamic Therapy in Treating Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors That Cannot Be Removed by Surgery

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder Cancer
University College, London 92
Early research (Phase 1)Looking for participantsNCT06058663
What this trial is testing

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaOligometastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Mayo Clinic 16
Testing effectiveness (Phase 2)UnknownNCT02162914
What this trial is testing

Regorafenib Versus Placebo to Treat Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma
Erasme University Hospital 66
Testing effectiveness (Phase 2)Looking for participantsNCT05655949
What this trial is testing

Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio

Who this might be right for
Bile Duct CancerCholangiocarcinomaCholangiocarcinoma Non-resectable+2 more
Beth Israel Deaconess Medical Center 30
Large-scale testing (Phase 3)Not Yet RecruitingNCT07765433
What this trial is testing

Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer

Who this might be right for
Locally Advanced Biliary Tract AdenocarcinomaLocally Advanced Extrahepatic CholangiocarcinomaLocally Advanced Intrahepatic Cholangiocarcinoma+12 more
ECOG-ACRIN Cancer Research Group
Testing effectiveness (Phase 2)Active Not RecruitingNCT04068194
What this trial is testing

Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies

Who this might be right for
Locally Advanced Malignant Solid NeoplasmLocally Advanced Unresectable CholangiocarcinomaLocally Advanced Unresectable Gallbladder Carcinoma+7 more
National Cancer Institute (NCI) 103
Testing effectiveness (Phase 2)Looking for participantsNCT05422690
What this trial is testing

The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer

Who this might be right for
Intrahepatic Cholangiocarcinoma
Inova Health Care Services 16
Early research (Phase 1)Study completedNCT04641871
What this trial is testing

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 78
Not applicableEnrolling By InvitationNCT04195503
What this trial is testing

Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma, Intrahepatic
University Health Network, Toronto 10
Not applicableNot Yet RecruitingNCT07326189
What this trial is testing

Preoperative Right Hepatic Artery Embolization for Locally Advanced Bismuth IIIb and IV Perihilar Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma Non-resectable
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 33
Testing effectiveness (Phase 2)Looking for participantsNCT07488676
What this trial is testing

ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

Who this might be right for
Gastric or Gastro-esophageal Junction (GEJ) AdenocarcinomaPancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 150
Testing effectiveness (Phase 2)Looking for participantsNCT07780838
What this trial is testing

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

Who this might be right for
Locally Advanced Ampulla of Vater CarcinomaLocally Advanced Biliary Tract CarcinomaLocally Advanced Extrahepatic Cholangiocarcinoma+20 more
Ohio State University Comprehensive Cancer Center 29
Testing effectiveness (Phase 2)Looking for participantsNCT06501625
What this trial is testing

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Who this might be right for
Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation
Institut de Recherches Internationales Servier 52
Testing effectiveness (Phase 2)Study completedNCT00033540
What this trial is testing

S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangiocarcinoma

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder Cancer
SWOG Cancer Research Network 57
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