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Results for “Locally Advanced Unresectable Malignant Solid Neoplasm”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Early research (Phase 1)Study completedNCT02536469
What this trial is testing

HuMax-IL8 (Interleukin8) in Patients With Advanced Malignant Solid Tumors

Who this might be right for
Solid Tumor
Bristol-Myers Squibb 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07537881
What this trial is testing

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC288 in the Treatment of Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 326
Testing effectiveness (Phase 2)Looking for participantsNCT07436728
What this trial is testing

TAK-505 in Adults With Solid Tumors

Who this might be right for
Malignant Solid Tumors
Takeda 151
Early research (Phase 1)Ended earlyNCT03878524
What this trial is testing

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAnatomic Stage IV Breast Cancer AJCC v8Anemia+47 more
OHSU Knight Cancer Institute 2
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Looking for participantsNCT05205850
What this trial is testing

RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 135
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+97 more
Mayo Clinic 132
Testing effectiveness (Phase 2)Looking for participantsNCT05564377
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Who this might be right for
Advanced Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+12 more
National Cancer Institute (NCI) 2,900
Early research (Phase 1)Looking for participantsNCT07137416
What this trial is testing

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast Carcinoma+13 more
National Cancer Institute (NCI) 36
Early research (Phase 1)Looking for participantsNCT06418061
What this trial is testing

Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
UnresectableLocally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 198
Testing effectiveness (Phase 2)Study completedNCT04121442
What this trial is testing

Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors

Who this might be right for
Solid Tumor, Adult
Buzzard Pharmaceuticals 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Looking for participantsNCT06038396
What this trial is testing

RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Looking for participantsNCT06016062
What this trial is testing

RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Solid Tumor
RemeGen Co., Ltd. 221
Early research (Phase 1)Looking for participantsNCT06364410
What this trial is testing

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+10 more
National Cancer Institute (NCI) 48
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
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