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Results for “Locally Advanced Unresectable Malignant Solid Neoplasm”

30 trials

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Showing 20 of 30 results

Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Testing effectiveness (Phase 2)Looking for participantsNCT07105215
What this trial is testing

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 312
Testing effectiveness (Phase 2)Looking for participantsNCT06016062
What this trial is testing

RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Solid Tumor
RemeGen Co., Ltd. 221
Testing effectiveness (Phase 2)Looking for participantsNCT06038396
What this trial is testing

RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Looking for participantsNCT05205850
What this trial is testing

RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 135
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Early research (Phase 1)Study completedNCT03238027
What this trial is testing

Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Who this might be right for
Solid TumorMetastatic TumorLocally Advanced Malignant Neoplasm+1 more
Syndax Pharmaceuticals 45
Testing effectiveness (Phase 2)Study completedNCT01902173
What this trial is testing

Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmLocally Advanced Malignant Solid NeoplasmLocally Advanced Melanoma+6 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Study completedNCT04121442
What this trial is testing

Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors

Who this might be right for
Solid Tumor, Adult
Buzzard Pharmaceuticals 15
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT05053971
What this trial is testing

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

Who this might be right for
Advanced Malignant Solid NeoplasmLocally Advanced Pancreatic CarcinomaMetastatic Pancreatic Carcinoma+6 more
National Cancer Institute (NCI) 49
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+127 more
Mayo Clinic 36
Early research (Phase 1)Study completedNCT00717704
What this trial is testing

Solid Tumors Using Ixabepilone and Dasatinib

Who this might be right for
Solid Tumor
Medstar Health Research Institute 19
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Early research (Phase 1)Looking for participantsNCT07137416
What this trial is testing

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast Carcinoma+13 more
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Ended earlyNCT04387071
What this trial is testing

CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Pancreatic AdenocarcinomaStage IV Pancreatic Cancer AJCC v8+1 more
University of Southern California 2
Early research (Phase 1)Temporarily pausedNCT06364410
What this trial is testing

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+10 more
National Cancer Institute (NCI) 48
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
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